Results 81 to 90 of about 405 (139)
Kaposi’s sarcoma-associated herpesvirus ORF61 protein sequesters APOBEC3B in filamentous aggregates
Journal of VirologyHerpesviruses are large DNA viruses that encode homologs of cellular enzymes. The viral ribonucleotide reductase, which consists of large R1 and small R2 subunits, is required for deoxyribonucleotide synthesis.
Laura-Marie Luoto +4 more
doaj +1 more source
PLoS ONE, 2020 Rhesus macaque (RM) rhadinovirus (RRV) is a simian gamma-2 herpesvirus closely related to human Kaposi's sarcoma-associated herpesvirus (KSHV). RRV is associated with the development of diseases in simian immunodeficiency virus (SIV) co-infected RM that ...
Ryan Douglas Estep +7 more
doaj +1 more source
Clinical and Translational Medicine, Volume 14, Issue 7, July 2024.DETECTOR‐seq (depletion‐assisted multiplexed cell‐free total RNA sequencing) enabled efficient and specific depletion of sequences derived from fragmented ribosomal and mitochondrial RNAs in plasma. Distinct human and microbial cell‐free RNA (cfRNA) signatures in whole Plasma versus extracellular vesicles (EVs) were revealed.
Hongke Wang +13 more
wiley +1 more source
FUNCTIONAL CHARACTERIZATION OF THE VIRAL FLICE INHIBITORY PROTEIN OF RHESUS MONKEY RHADINOVIRUS [PDF]
, 2011 Rhesus monkey rhadinovirus (RRV) is a gamma-2 herpesvirus closely related to Kaposi's sarcoma-associated herpesvirus (KSHV). KSHV is associated with several malignant diseases, including Kaposi's sarcoma, primary effusion lymphoma and multicentric ...
Ritthipichai, Krit
core +1 more source
Gammaherpesvirus RNAs Come Full Circle
mBio, 2019 After an adaptive immune response is mounted, gammaherpesviruses achieve persistence through the utilization of viral noncoding RNAs to craft a suitable host cell environment in an immunologically transparent manner. While gammaherpesvirus long noncoding
Nathan A. Ungerleider +3 more
doaj +1 more source
Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses
Ecology and Evolution, Volume 14, Issue 6, June 2024.We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Anna R. Sjodin +3 more
wiley +1 more source
Journal of VirologyHerpesviruses encode multiple factors that disarm innate immune signaling to evade host anti-viral responses. Several viral microRNAs expressed by Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) disrupt the induction of type I
Devin N. Fachko +8 more
doaj +1 more source
Two herpesviral noncoding PAN RNAs are functionally homologous but do not associate with common chromatin loci. [PDF]
PLoS Pathogens, 2018 During lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV), a nuclear viral long noncoding RNA known as PAN RNA becomes the most abundant polyadenylated transcript in the cell. Knockout or knockdown of KSHV PAN RNA results in loss of late
Johanna B Withers +4 more
doaj +1 more source
Experimental rhadinovirus infection in juvenile macaque K04199.
, 2018 The naïve juvenile pig-tailed macaque K04199 was inoculated intravenously with diluted, filtered saliva from the 98039 cynomolgus macaque donor (Saliva C) containing high levels of the RV1 rhadinovirus (RFHVMf), and was inoculated into the cheek pouches (
Serge Barcy (129971) +6 more
core +1 more source
Interaction of gamma-herpesvirus genome maintenance proteins with cellular chromatin.
PLoS ONE, 2013 The capacity of gamma-herpesviruses to establish lifelong infections is dependent on the expression of genome maintenance proteins (GMPs) that tether the viral episomes to cellular chromatin and allow their persistence in latently infected proliferating ...
Nouman Mughal +4 more
doaj +1 more source