Results 61 to 70 of about 405 (139)

First description of a herpesvirus infection in genus Lepus.

open access: yesPLoS ONE, 2020
During the necropsies of Iberian hares obtained in 2018/2019, along with signs of the nodular form of myxomatosis, other unexpected external lesions were also observed.
F A Abade dos Santos   +8 more
doaj   +1 more source

Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family [PDF]

open access: yesJournal of Virology, 2016
ABSTRACT Japanese macaque (JM) rhadinovirus (JMRV) is a novel, gamma-2 herpesvirus that was recently isolated from JM with inflammatory demyelinating encephalomyelitis (JME). JME is a spontaneous and chronic disease with clinical characteristics and immunohistopathology comparable to those of multiple sclerosis in humans.
Rebecca L, Skalsky   +5 more
openaire   +2 more sources

Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposi’s Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell-Specific Manner

open access: yesmBio, 2021
The interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral proteins that inhibit the entry of enveloped viruses. We analyzed the effect of IFITMs on the gamma-2 herpesviruses Kaposi’s sarcoma-associated herpesvirus (KSHV) and the
Bojan F. Hörnich   +4 more
doaj   +1 more source

qPCR Screen for RV1 and RV2 rhadinovirus DNA in saliva.

open access: yes, 2018
Saliva was obtained from macaques at the WaNPRC undergoing routine health screening and tested for the presence of RV1 and RV2 rhadinovirus DNA. A) The highest RV1 and RV2 DNA levels detected during longitudinal screening.
Serge Barcy (129971)   +6 more
core   +1 more source

Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice. [PDF]

open access: yesPLoS Pathogens, 2018
Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the role of these viral FGARATs (vFGARATs) in the pathogenesis of a natural host has not been ...
Nick D Van Skike   +11 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

Experimental rhadinovirus infection in juvenile macaque M04203.

open access: yes, 2018
The naïve juvenile pig-tailed macaque M04203 was inoculated intravenously (i.v.) with diluted filtered saliva from the 01019 cynomolgus macaque donor (Saliva “A”) containing high levels of RFHVMf and low levels of MfaLCV and was inoculated into the cheek
Serge Barcy (129971)   +6 more
core   +1 more source

Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections

open access: yesTumour Virus Research, 2021
Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their reactivation instigates dreadful diseases from cancer ...
Annu Rani   +4 more
doaj   +1 more source

Model Systems of Gammaherpesvirus Infection, Immunity, and Disease

open access: yesJournal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT Epstein‐Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) are oncogenic human gammaherpesviruses (GHVs) associated with a broad spectrum of malignancies and chronic diseases. However, direct studies of these viruses in humans are limited by ethical constraints, technical challenges, and their strict species specificity.
Arundhati Gupta   +3 more
wiley   +1 more source

Cytokines in Endocrine Dysfunction of Plasma Cell Disorders

open access: yesMediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
Monoclonal gammopathies (MG) are classically associated with lytic bone lesions, hypercalcemia, anemia, and renal insufficiency. However, in some cases, symptoms of endocrine dysfunction are more prominent than these classical signs and misdiagnosis can thus be possible.
Eva Feigerlová   +2 more
wiley   +1 more source

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