Results 61 to 70 of about 405 (139)
First description of a herpesvirus infection in genus Lepus.
During the necropsies of Iberian hares obtained in 2018/2019, along with signs of the nodular form of myxomatosis, other unexpected external lesions were also observed.
F A Abade dos Santos +8 more
doaj +1 more source
Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family [PDF]
ABSTRACT Japanese macaque (JM) rhadinovirus (JMRV) is a novel, gamma-2 herpesvirus that was recently isolated from JM with inflammatory demyelinating encephalomyelitis (JME). JME is a spontaneous and chronic disease with clinical characteristics and immunohistopathology comparable to those of multiple sclerosis in humans.
Rebecca L, Skalsky +5 more
openaire +2 more sources
The interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral proteins that inhibit the entry of enveloped viruses. We analyzed the effect of IFITMs on the gamma-2 herpesviruses Kaposi’s sarcoma-associated herpesvirus (KSHV) and the
Bojan F. Hörnich +4 more
doaj +1 more source
qPCR Screen for RV1 and RV2 rhadinovirus DNA in saliva.
Saliva was obtained from macaques at the WaNPRC undergoing routine health screening and tested for the presence of RV1 and RV2 rhadinovirus DNA. A) The highest RV1 and RV2 DNA levels detected during longitudinal screening.
Serge Barcy (129971) +6 more
core +1 more source
Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice. [PDF]
Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the role of these viral FGARATs (vFGARATs) in the pathogenesis of a natural host has not been ...
Nick D Van Skike +11 more
doaj +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Experimental rhadinovirus infection in juvenile macaque M04203.
The naïve juvenile pig-tailed macaque M04203 was inoculated intravenously (i.v.) with diluted filtered saliva from the 01019 cynomolgus macaque donor (Saliva “A”) containing high levels of RFHVMf and low levels of MfaLCV and was inoculated into the cheek
Serge Barcy (129971) +6 more
core +1 more source
Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their reactivation instigates dreadful diseases from cancer ...
Annu Rani +4 more
doaj +1 more source
Model Systems of Gammaherpesvirus Infection, Immunity, and Disease
ABSTRACT Epstein‐Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) are oncogenic human gammaherpesviruses (GHVs) associated with a broad spectrum of malignancies and chronic diseases. However, direct studies of these viruses in humans are limited by ethical constraints, technical challenges, and their strict species specificity.
Arundhati Gupta +3 more
wiley +1 more source
Cytokines in Endocrine Dysfunction of Plasma Cell Disorders
Monoclonal gammopathies (MG) are classically associated with lytic bone lesions, hypercalcemia, anemia, and renal insufficiency. However, in some cases, symptoms of endocrine dysfunction are more prominent than these classical signs and misdiagnosis can thus be possible.
Eva Feigerlová +2 more
wiley +1 more source

