Modeling the response of an endangered rabbit population to RHDV2 and vaccination
Conservation Science and PracticeRabbit hemorrhagic disease virus 2 (RHDV2), recently detected in the western United States, has the potential to cause mass mortality events in wild rabbit and hare populations. Currently, few management strategies exist other than vaccination.
Robin E. Russell +5 more
doaj +3 more sources
Epidemiological characterization and risk assessment of rabbit haemorrhagic disease virus 2 (RHDV2/b/GI.2) in the world [PDF]
Veterinary ResearchA novel variant of rabbit haemorrhagic disease virus, designated RHDV2/b/GI.2, was first discovered in France in 2010. Subsequently, RHDV2 rapidly spread to Africa, North America, Australia, and Asia. RHDV2 outbreaks have resulted in significant economic
Zhuo Sun +4 more
doaj +5 more sources
EcosphereInfectious diseases can cause considerable mortality in vertebrate populations, especially when a new pathogen emerges. Quantifying the impact of diseases on wild populations and dissecting the underlying mechanisms requires longitudinal individual ...
Jérôme Letty +7 more
doaj +4 more sources
Age and Infectious Dose Significantly Affect Disease Progression after RHDV2 Infection in Naïve Domestic Rabbits [PDF]
Viruses, 2021 Rabbit haemorrhagic disease virus 2 (RHDV2 or GI.2, referring to any virus with lagovirus GI.2 structural genes) is a recently emerged calicivirus that causes generalised hepatic necrosis and disseminated intravascular coagulation leading to death in ...
Robyn N Hall +2 more
exaly +6 more sources
Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare [PDF]
Virus ResearchThe genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis ...
Patrizia Cavadini +4 more
doaj +5 more sources
An RT-qPCR Assay from Rectal Swabs for the Detection of Rabbit Hemorrhagic Disease Virus 2 in Natural Cases. [PDF]
Transbound Emerg Dis, 2023 Rabbit hemorrhagic disease virus 2 (RHDV2 or Lagovirus europaeus GI.2) is spreading across North America. This has enabled submissions of lagomorphs for testing to veterinary diagnostic laboratories (VDLs). The liver is currently the gold‐standard sample type for testing by RT‐qPCR.
Asin J +6 more
europepmc +2 more sources
Viruses, 2019 Rabbit haemorrhagic disease virus (RHDV) type 2 (GI.2/RHDV2/b) is an emerging pathogen in wild rabbits and in domestic rabbits vaccinated against RHDV (GI.1).
Qiuhong Miao, Jooske Ijzer, Jie Zhu
exaly +3 more sources
Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]
VirusesRabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu +5 more
doaj +2 more sources
Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious [PDF]
Vaccines, 2023 Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen.
Bassel Akache +16 more
doaj +2 more sources
Practical Suggestions for Assessing Rabbit Haemorrhagic Disease Virus 2 Risk to Endangered Native Lagomorphs in North America and Southern Africa [PDF]
VirusesA new form of the rabbit haemorrhagic disease virus, RHDV2, first observed in European rabbits, has spread widely among different species of hares in Europe, jackrabbits and cottontails in North America, and hares in southern Africa.
Brian Cooke
doaj +2 more sources