Results 131 to 140 of about 166,738 (337)
Coding Sequence Density Estimation Via Topological Pressure [PDF]
arXiv, 2011 We give a new approach to coding sequence (CDS) density estimation in genomic analysis based on the topological pressure, which we develop from a well known concept in ergodic theory. Topological pressure measures the "weighted information content" of a finite word, and incorporates 64 parameters which can be interpreted as a choice of weight for each ...
arxiv
Infection and Immunity, 2017 In the past 2 decades, it has become increasingly clear that nonhuman primates, specifically macaques, are useful models for human tuberculosis (TB). Several macaque species have been used for TB studies, and questions remain about the similarities and ...
Pauline Maiello +6 more
semanticscholar +1 more source
Cell Proliferation, EarlyView.Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li +10 more
wiley +1 more source
Computationally efficient model selection for joint spikes and waveforms decoding [PDF]
arXiv, 2018 A recent paradigm for decoding behavioral variables or stimuli from neuron ensembles relies on joint models for electrode spike trains and their waveforms, which, in principle, is more efficient than decoding from electrode spike trains alone or from sorted neuron spike trains.
arxiv
Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques
PLoS ONE, 2017 Animal models of Zika virus (ZIKV) are needed to better understand tropism and pathogenesis and to test candidate vaccines and therapies to curtail the pandemic.
Lark L. Coffey +24 more
semanticscholar +1 more source
Cell Proliferation, EarlyView.Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang +23 more
wiley +1 more source
Hand Musculature of the Rhesus Monkey (Macaca mulatta): An Anatomical Study
AnatomiaThe rhesus monkey (Macaca mulatta) is one of the most frequently used primate species in biomedical research. As a common animal model used to study human disease, the validation of the obtained research data depends on a solid understanding of rhesus ...
Christophe Casteleyn +2 more
doaj +1 more source
Analysis of evolutionary origins of genomic loci harboring 59,732 candidate human-specific regulatory sequences identifies genetic divergence patterns during evolution of Great Apes [PDF]
arXiv, 2018 Our view of the universe of genomic regions harboring various types of candidate human-specific regulatory sequences (HSRS) has been markedly expanded in recent years. To infer the evolutionary origins of loci harboring HSRS, analyses of conservations patterns of 59,732 loci in Modern Humans, Chimpanzee, Bonobo, Gorilla, Orangutan, Gibbon, and Rhesus ...
arxiv
Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys
Nature, 2014 The viral reservoir represents a critical challenge for human immunodeficiency virus type 1 (HIV-1) eradication strategies. However, it remains unclear when and where the viral reservoir is seeded during acute infection and the extent to which it is ...
J. Whitney +25 more
semanticscholar +1 more source