Results 151 to 160 of about 166,738 (337)

Modulation of Sodium and Ammonia Transporters in the Context of Viral Gill Diseases in Common Carp (Cyprinus carpio)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Osmoregulation and ammonia removal are among key physiological processes that take place in gills and affect fish homeostasis and well‐being. These processes can be disrupted by numerous environmental factors, but also by viral infections, especially those leading to severe gill disorders.
Maria Zawisza   +5 more
wiley   +1 more source

Automated identification of neurons and their locations [PDF]

open access: yesarXiv, 2007
Individual locations of many neuronal cell bodies (>10^4) are needed to enable statistically significant measurements of spatial organization within the brain such as nearest-neighbor and microcolumnarity measurements. In this paper, we introduce an Automated Neuron Recognition Algorithm (ANRA) which obtains the (x,y) location of individual neurons ...
arxiv  

Early Emergence of Metacognition in Rhesus Monkeys. [PDF]

open access: yesDev Sci
ABSTRACT Metacognition, or monitoring and controlling one's knowledge, is a key feature of human cognition. Accumulating evidence shows that foundational forms of metacognition are already present in young infants and then scaffold later‐emerging skills. Although many animals exhibit cognitive processes relevant to metacognition, it is unclear if other
Huang Y, Rosati AG.
europepmc   +2 more sources

Pharmacokinetics of GS‐441524 following intravenous remdesivir in six cats and results of therapeutic drug monitoring during treatment of feline infectious peritonitis: 22 cases (2021–2024)

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives This study aimed to: (1) characterise the pharmacokinetics of GS‐441524 following intravenous (iv) administration of 15 mg/kg remdesivir (RDV) in client‐owned cats with feline infectious peritonitis (FIP); (2) document plasma protein binding of GS‐441524 in cats; (3) determine whether trough GS‐441524 plasma concentrations predict ‘simple ...
S. J. Coggins   +6 more
wiley   +1 more source

Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa   +12 more
wiley   +1 more source

Myopia control using a modified optical defocus soft contact lens in schoolchildren—A 12‐month randomised double masked control trial

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose Defocus Incorporated Soft Contact (DISC) lenses with +2.50 D myopic defocus reduced myopia progression by 25% in a previous randomised clinical trial (RCT). The current study aimed to evaluate if a stronger myopic defocus, +3.50 D with variable myopic defocus (DISC3.5plus), could slow myopia progression compared with single vision (SV)
Hanyu Zhang   +8 more
wiley   +1 more source

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