Results 11 to 20 of about 166,738 (337)
Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride
Laboratory Animal Research, 2019 Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited.Bon-Sang Koo, Dong-Ho Lee, Philyong Kang, Kang-Jin Jeong, Sangil Lee, Kijin Kim, Youngjeon Lee, Jae-Won Huh, Young-Hyun Kim, Sang-Je Park, Yeung Bae Jin, Sun-Uk Kim, Ji-Su Kim, Yeonghoon Son, Sang-Rae Lee +14 moredoaj +2 more sourcesHypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques
Nature Biotechnology, 2023 A genetic method to block immune rejection of allogeneic cells is validated in monkeys. Genetic engineering of allogeneic cell therapeutics that fully prevents rejection by a recipient’s immune system would abolish the requirement for immunosuppressive ...Xiaomeng Hu, K. White, Ari G. Olroyd, Rowena deJesus, Antonia A Dominguez, W. Dowdle, A. Friera, C. Young, Frank Wells, Elaine Y. Chu, C. Ito, Harini Krishnapura, Surbhi Jain, Ramya Ankala, T. Mcgill, A. Lin, Kyla Egenberger, Allison Gagnon, J. Michael Rukstalis, N. Hogrebe, Corie Gattis, R. Basco, J. Millman, P. Kievit, Mark M. Davis, L. Lanier, A. Connolly, T. Deuse, S. Schrepfer +28 moresemanticscholar +1 more sourceDNA vaccine protection against SARS-CoV-2 in rhesus macaques
Science, 2020 Prototype DNA vaccines for SARS-CoV-2 The development of a vaccine to protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an urgent biomedical need. Yu et al.Jingyou Yu, Lisa H. Tostanoski, Lauren Peter, N. Mercado, K. McMahan, S. Mahrokhian, Joseph P. Nkolola, Jinyan Liu, Zhenfeng Li, A. Chandrashekar, David R. Martinez, C. Loos, C. Atyeo, S. Fischinger, J. Burke, Matthew D. Slein, Yuezhou Chen, Adam Zuiani, Felipe J. N. Lelis, M. Travers, S. Habibi, Laurent Pessaint, Alex Van Ry, Kelvin Blade, Renita Brown, Anthony L. Cook, Brad Finneyfrock, A. Dodson, Elyse Teow, Jason Velasco, R. Zahn, F. Wegmann, E. Bondzie, Gabriel Dagotto, M. Gebre, Xuan He, C. Jacob-Dolan, Marinela Kirilova, N. Kordana, Zijin Lin, Lori F. Maxfield, Felix Nampanya, Ramya Nityanandam, John D. Ventura, H. Wan, Yongfei Cai, Bing Chen, A. Schmidt, D. Wesemann, R. Baric, G. Alter, H. Andersen, M. Lewis, D. Barouch +53 moresemanticscholar +1 more sourceCorrelates of Protection Against SARS-CoV-2 in Rhesus Macaques
Nature, 2020 Recent studies have reported the protective efficacy of both natural1 and vaccine-induced2–7 immunity against challenge with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques.K. McMahan, Jingyou Yu, N. Mercado, C. Loos, Lisa H. Tostanoski, A. Chandrashekar, Jinyan Liu, Lauren Peter, C. Atyeo, A. Zhu, E. Bondzie, Gabriel Dagotto, M. Gebre, C. Jacob-Dolan, Zhenfeng Li, Felix Nampanya, Shivani Patel, Laurent Pessaint, Alex Van Ry, Kelvin Blade, J. Yalley-Ogunro, M. Cabus, Renita Brown, Anthony L. Cook, Elyse Teow, H. Andersen, M. Lewis, D. Lauffenburger, G. Alter, D. Barouch +29 moresemanticscholar +1 more sourceOrexinergic neurons in the hypothalami of an Asiatic lion, an African lion, and a Southeast African cheetah
Journal of Comparative Neurology, Volume 531, Issue 3, Page 366-389, February 2023., 2023 Photomicrograph of orexinergic neurons forming the main orexinergic neuronal cluster in the hypothalamus of a Southeast African cheetah. While showing the standard features of the orexinergic system, the Southeast African cheetah, along with an Asiatic and an African lion, also exhibits specializations in the organization of this system.Demi Oddes, Ayanda Ngwenya, Illke B. Malungo, Anita Burkevica, Therese Hård, Mads. F. Bertelsen, Muhammad A. Spocter, D. Michael Scantlebury, Paul R. Manger +8 morewiley +1 more sourceSARS-CoV-2 infection protects against rechallenge in rhesus macaques
Science, 2020 Immunity from reinfection One of the many open questions about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is whether an individual who has cleared the virus can be infected a second time and get sick. Chandrashekar et al.A. Chandrashekar, Jinyan Liu, Amanda J. Martinot, K. McMahan, N. Mercado, Lauren Peter, Lisa H. Tostanoski, Jingyou Yu, Z. Maliga, M. Nekorchuk, K. Busman-Sahay, Margaret Terry, Linda M. Wrijil, Sarah Ducat, David R. Martinez, C. Atyeo, S. Fischinger, J. Burke, Matthew D. Slein, Laurent Pessaint, Alex Van Ry, J. Greenhouse, Tammy Taylor, Kelvin Blade, Anthony L. Cook, Brad Finneyfrock, Renita Brown, Elyse Teow, Jason Velasco, R. Zahn, F. Wegmann, P. Abbink, E. Bondzie, Gabriel Dagotto, M. Gebre, Xuan He, C. Jacob-Dolan, N. Kordana, Zhenfeng Li, M. Lifton, S. Mahrokhian, Lori F. Maxfield, Ramya Nityanandam, Joseph P. Nkolola, A. Schmidt, Andrew D. Miller, R. Baric, G. Alter, P. Sorger, J. Estes, H. Andersen, M. Lewis, D. Barouch +52 moresemanticscholar +1 more sourceCortical synapses of the world's smallest mammal: An FIB/SEM study in the Etruscan shrew
Journal of Comparative Neurology, Volume 531, Issue 3, Page 390-414, February 2023., 2023 The present work provides a quantitative dataset of synapses from the Etruscan shrew (the smallest known terrestrial mammal). We have identified common and differing principles of synaptic organization compared to other mammalian species. Abstract
The main aim of the present study was to determine if synapses from the exceptionally small brain of the ...Lidia Alonso‐Nanclares, J. Rodrigo Rodríguez, Angel Merchan‐Perez, Juncal González‐Soriano, Sergio Plaza‐Alonso, Nicolás Cano‐Astorga, Robert K. Naumann, Michael Brecht, Javier DeFelipe +8 morewiley +1 more sourceProphylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Middle East Respiratory Syndrome, caused by the MERS coronavirus (MERS-CoV), continues to cause severe respiratory disease with a high case fatality rate.E. de Wit, F. Feldmann, Jacqueline Cronin, R. Jordan, A. Okumura, T. Thomas, D. Scott, T. Cihlář, H. Feldmann +8 moresemanticscholar +1 more sourceComparison of rhesus and cynomolgus macaques as an infection model for COVID-19
Nature Communications, 2021 A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis of emerging diseases and to assess the safety ...F. Salguero, A. White, Gillian S. Slack, S. Fotheringham, K. Bewley, K. Gooch, S. Longet, H. Humphries, Robert J. Watson, L. Hunter, K. Ryan, Y. Hall, L. Sibley, C. Sarfas, Lauren Allen, M. Aram, Emily Brunt, Phillip J. Brown, K. Buttigieg, Breeze E. Cavell, R. Cobb, N. Coombes, A. Darby, O. Daykin-Pont, M. Elmore, Isabel García-Dorival, Konstantinos Gkolfinos, K. Godwin, Jade Gouriet, R. Halkerston, D. Harris, T. Hender, Catherine M. K. Ho, C. Kennard, Daniel Knott, Stephanie Leung, Vanessa Lucas, Adam Mabbutt, Alexandra L. Morrison, Charlotte Nelson, D. Ngabo, Jemma Paterson, E. Penn, S. Pullan, Irene Taylor, T. Tipton, Stephen R. Thomas, J. Tree, C. Turner, Edith E. Vamos, Nadina I. Wand, Nathan R. Wiblin, S. Charlton, Xiaofeng Dong, B. Hallis, G. Pearson, E. Rayner, A. Nicholson, S. Funnell, J. Hiscox, M. Dennis, F. Gleeson, S. Sharpe, M. Carroll +63 moresemanticscholar +1 more sourceREGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters
Science, 2020 A beneficial cocktail Since the start of the coronavirus disease 2019 (COVID-19) pandemic, considerable effort has gone into generating and characterizing neutralizing antibodies that could be used as therapeutics.A. Baum, D. Ajithdoss, R. Copin, A. Zhou, Kathryn Lanza, N. Negron, M. Ni, Yi Wei, Kusha A Mohammadi, B. Musser, G. Atwal, A. Oyejide, Yenny Goez-Gazi, John W Dutton, E. Clemmons, Hilary M Staples, Carmen Bartley, Benjamin Klaffke, K. Alfson, M. Gazi, O. Gonzalez, E. Dick, R. Carrion, Laurent Pessaint, Maciel Porto, Anthony L. Cook, Renita Brown, Vaneesha Ali, J. Greenhouse, Tammy Taylor, H. Andersen, M. Lewis, N. Stahl, A. Murphy, G. Yancopoulos, C. Kyratsous +35 moresemanticscholar +1 more source
