Results 31 to 40 of about 65,503 (295)

Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Chimeric antigen receptor (CAR)-T cells show great promise in treating cancers and viral infections. However, most protocols developed to expand T cells require relatively long periods of time in culture, potentially leading to progression toward ...
Mary S. Pampusch   +7 more
doaj   +1 more source

Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis)

open access: yesBMC Genomics, 2022
Background Cynomolgus macaque (Macaca fascicularis) is an attractive animal model for the study of human disease and is extensively used in biomedical research.
Swati Jaiswal   +14 more
doaj   +1 more source

Abnormal early cleavage events predict early embryo demise: sperm oxidative stress and early abnormal cleavage. [PDF]

open access: yes, 2014
Human embryos resulting from abnormal early cleavage can result in aneuploidy and failure to develop normally to the blastocyst stage. The nature of paternal influence on early embryo development has not been directly demonstrated although many studies ...
Barker, Christopher M   +4 more
core   +2 more sources

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

open access: yesBMC Genetics, 2012
Background As a model organism in biomedicine, the rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate. Although a draft genome sequence was completed in 2007, there has been no systematic genome-wide comparison of genetic variation ...
Yuan Qiaoping   +12 more
doaj   +1 more source

The Subcortical Atlas of the Rhesus Macaque (SARM) for neuroimaging

open access: yesNeuroImage, 2021
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing functional networks identified by neuroimaging techniques.
Renée Hartig   +7 more
doaj   +1 more source

Pooled genomic indexing of rhesus macaque [PDF]

open access: yesGenome Research, 2005
Pooled genomic indexing (PGI) is a method for mapping collections of bacterial artificial chromosome (BAC) clones between species by using a combination of clone pooling and DNA sequencing. PGI has been used to map a total of 3858 BAC clones covering ∼24% of the rhesus macaque (Macaca mulatta) genome onto 4178 homologous loci in the human genome.
Aleksandar, Milosavljevic   +12 more
openaire   +2 more sources

Persistent effects of early infant diet and associated microbiota on the juvenile immune system. [PDF]

open access: yes, 2015
Early infant diet has significant impacts on the gut microbiota and developing immune system. We previously showed that breast-fed and formula-fed rhesus macaques develop significantly different gut microbial communities, which in turn are associated ...
Ardeshir, Amir   +5 more
core   +1 more source

An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts

open access: yesStem Cell Research, 2017
The rhesus macaque induced pluripotent stem cell (riPSC) line, UCLAi090-A (riPSC90), was generated from rhesus embryonic fibroblast (REF) cells called REF90.
Enrique Sosa   +6 more
doaj   +1 more source

Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies

open access: yesFrontiers in Immunology, 2017
The rhesus macaque is a critically important animal model in biomedical research, most recently playing a key role in the development of vaccines against human immunodeficiency virus-1.
Akshaya Ramesh   +11 more
doaj   +1 more source

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