Results 41 to 50 of about 121,420 (191)

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

BMC Genetics, 2012
Background As a model organism in biomedicine, the rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate. Although a draft genome sequence was completed in 2007, there has been no systematic genome-wide comparison of genetic variation ...
Yuan Qiaoping, Zhou Zhifeng, Lindell Stephen G, Higley J, Ferguson Betsy, Thompson Robert C, Lopez Juan F, Suomi Stephen J, Baghal Basel, Baker Maggie, Mash Deborah C, Barr Christina S, Goldman David   +12 more
doaj   +1 more source

Pooled genomic indexing of rhesus macaque [PDF]

Genome Research, 2005
Pooled genomic indexing (PGI) is a method for mapping collections of bacterial artificial chromosome (BAC) clones between species by using a combination of clone pooling and DNA sequencing. PGI has been used to map a total of 3858 BAC clones covering ∼24% of the rhesus macaque (Macaca mulatta) genome onto 4178 homologous loci in the human genome.
Aleksandar, Milosavljevic, Ronald A, Harris, Erica J, Sodergren, Andrew R, Jackson, Ken J, Kalafus, Anne, Hodgson, Andrew, Cree, Weilie, Dai, Miklos, Csuros, Baoli, Zhu, Pieter J, de Jong, George M, Weinstock, Richard A, Gibbs   +12 more
openaire   +2 more sources

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Nature Communications, 2018
Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque
Enrique Sosa, Di Chen, Ernesto J. Rojas, Jon D. Hennebold, Karen A. Peters, Zhuang Wu, Truong N. Lam, Jennifer M. Mitchell, Meena Sukhwani, Ramesh C. Tailor, Marvin L. Meistrich, Kyle E. Orwig, Gunapala Shetty, Amander T. Clark   +13 more
doaj   +1 more source

An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts

Stem Cell Research, 2017
The rhesus macaque induced pluripotent stem cell (riPSC) line, UCLAi090-A (riPSC90), was generated from rhesus embryonic fibroblast (REF) cells called REF90.
Enrique Sosa, Rachel Kim, Ernesto J. Rojas, Linzi Hosohama, Jon D. Hennebold, Kyle E. Orwig, Amander T. Clark   +6 more
doaj   +1 more source

Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs. [PDF]

PLoS Genetics, 2012
Tinkering with pre-existing genes has long been known as a major way to create new genes. Recently, however, motherless protein-coding genes have been found to have emerged de novo from ancestral non-coding DNAs.
Chen Xie, Yong E Zhang, Jia-Yu Chen, Chu-Jun Liu, Wei-Zhen Zhou, Ying Li, Mao Zhang, Rongli Zhang, Liping Wei, Chuan-Yun Li   +9 more
doaj   +1 more source

Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants

Nature Communications, 2019
We present a high-quality de novo genome assembly (rheMacS) of the Chinese rhesus macaque (Macaca mulatta) using long-read sequencing and multiplatform scaffolding approaches.
Yaoxi He, Xin Luo, Bin Zhou, Ting Hu, Xiaoyu Meng, P. Audano, Zev N. Kronenberg, E. Eichler, Jie Jin, Yongbo Guo, Yanan Yang, X. Qi, B. Su   +12 more
semanticscholar   +1 more source

Single nucleotide polymorphisms (SNPs) are highly conserved in rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques

BMC Genomics, 2007
Background Macaca fascicularis (cynomolgus or longtail macaques) is the most commonly used non-human primate in biomedical research. Little is known about the genomic variation in cynomolgus macaques or how the sequence variants compare to those of the ...
Kyes Randall C, Street Summer L, Grant Richard, Ferguson Betsy   +3 more
doaj   +1 more source

Neutrophil progenitor populations of rhesus macaques [PDF]

Journal of Leukocyte Biology, 2018
Abstract Captive-bred rhesus macaques of Indian origin represent one of the most important large animal models for infectious disease, solid organ transplantation, and stem cell research. There is a dearth of information defining hematopoietic development, including neutrophil leukocyte differentiation in this species using multicolor ...
Kim L, Weisgrau, Logan J, Vosler, Nicholas L, Pomplun, Jennifer M, Hayes, Heather A, Simmons, Kristen R, Friedrichs, Eva G, Rakasz   +6 more
openaire   +2 more sources

Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

Nature Communications, 2019
Calcium imaging is a powerful tool for recording from large populations of neurons in vivo. Imaging in rhesus macaque motor cortex can enable the discovery of fundamental principles of motor cortical function and can inform the design of next generation ...
Eric M. Trautmann, D. O’Shea, Xulu Sun, James H. Marshel, A. Crow, Brian Hsueh, Sam Vesuna, Lucas Cofer, G. Bohner, William E. Allen, Isaac Kauvar, S. Quirin, Matthew J. MacDougall, Yuzhi Chen, Matthew P. Whitmire, C. Ramakrishnan, M. Sahani, E. Seidemann, S. Ryu, K. Deisseroth, K. Shenoy   +20 more
semanticscholar   +1 more source

Rhesus macaque tetherin genotypes.

, 2020
The tetherin alelles identified in each of the rhesus macaques included in this study (middle) are listed next to their corresponding animal identification numbers (left) and the virus (SIVmac239 or SIVmac239AAA) each animal was infected with (right ...
Aidin Tavakoli-Tameh, S. Janaka, Katie R. Zarbock, Shelby L. O’Connor, K. Crosno, Saverio Capuano rd, Hajime Uno, J. Lifson, David T. Evans   +8 more
semanticscholar   +1 more source