Results 81 to 90 of about 241,326 (244)

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Purified Immunoglobulin F(ab′) 2 Prevents Lethal Staphylococcal Enterotoxin B Intoxication in Mice and Rhesus Monkeys

open access: yesZoonoses
Staphylococcal enterotoxin B (SEB), an exotoxin produced by single- or multi-drug-resistant Staphylococcus aureus ( S. aureus ), can induce food poisoning and toxic shock syndrome.
Jing Liu   +7 more
doaj   +1 more source

Reprogramming mechanism dissection and trophoblast replacement application in monkey somatic cell nuclear transfer

open access: yesNature Communications
Somatic cell nuclear transfer (SCNT) successfully clones cynomolgus monkeys, but the efficiency remains low due to a limited understanding of the reprogramming mechanism. Notably, no rhesus monkey has been cloned through SCNT so far. Our study conducts a
Zhaodi Liao   +12 more
doaj   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington   +4 more
wiley   +1 more source

An appropriate loading control for western blot analysis in animal models of myocardial ischemic infarction

open access: yesBiochemistry and Biophysics Reports, 2017
An appropriate loading control is critical for Western blot analysis. Housekeeping proteins (HKPs), such as β-actin, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and β-tubulin, are commonly used to normalize protein expression.
Xin Nie   +5 more
doaj   +1 more source

Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes

open access: yesJournal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas   +7 more
wiley   +1 more source

Global Stereopsis in Rhesus Monkeys

open access: yesQuarterly Journal of Experimental Psychology, 1975
In three separate experiments an attempt was made to demonstrate global stereopsis in two rhesus monkeys by using random dot stereograms projected and viewed through polarizing filters. Although both animals learned a number of discriminations, control tests showed that both were perceiving non-depth cues such as monocular identification of minute ...
Cowey, A, Parkinson, A, Warnick, L
openaire   +3 more sources

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal   +4 more
wiley   +1 more source

Sleeve bridging of the rhesus monkey ulnar nerve with muscular branches of the pronator teres: multiple amplification of axonal regeneration

open access: yesNeural Regeneration Research, 2015
Multiple-bud regeneration, i.e., multiple amplification, has been shown to exist in peripheral nerve regeneration. Multiple buds grow towards the distal nerve stump during proximal nerve fiber regeneration.
Yu-hui Kou   +8 more
doaj   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong   +3 more
wiley   +1 more source

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