Results 31 to 40 of about 268,778 (321)

c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. [PDF]

open access: yes, 2012
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are activated by environmental stress. JNK is also activated by proinflammatory cytokines, such as TNF and IL-1, and Toll-like receptor ligands ...
Firestein, Gary S, Guma, Monica
core   +1 more source

The Role of Extracellular Matrix and Hydrogels in Mesenchymal Stem Cell Chondrogenesis and Cartilage Regeneration

open access: yesLife, 2022
Diseases associated with articular cartilage disintegration or loss are still therapeutically challenging. The traditional treatment approaches only alleviate the symptoms while potentially causing serious side effects. The limited self-renewal potential
Magdalena Strecanska   +3 more
doaj   +1 more source

HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]

open access: yes, 2003
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena   +5 more
core   +2 more sources

Effectiveness of bazedoxifene in preventing glucocorticoid-induced bone loss in rheumatoid arthritis patients

open access: yesArthritis Research & Therapy, 2021
Objective To evaluate the effectiveness of bazedoxifene in preventing bone loss in patients with rheumatoid arthritis (RA) receiving low-dose glucocorticoids (GCs).
Soo-Kyung Cho   +6 more
doaj   +1 more source

Estimating the burden of rheumatoid arthritis in Africa:A systematic analysis [PDF]

open access: yes, 2012
Rheumatoid arthritis (RA) has an estimated worldwide prevalence of 1%. It is one of the leading causes of chronic morbidity in the developed world, but little is known about the disease burden in Africa. RA is often seen as a minor health problem and has
Abdel-Nasser   +32 more
core   +2 more sources

IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis

open access: yesArthritis Research & Therapy, 2018
Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo   +9 more
doaj   +1 more source

Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

open access: yesBMC Sports Science, Medicine and Rehabilitation, 2023
Background Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed
Kristine Røren Nordén   +10 more
doaj   +1 more source

Role of Nigella sativa in the Management of Osteoarthritis: A Systematic Review

open access: yesTraditional and Integrative Medicine, 2023
Because of the anti-inflammatory properties of thymoquinone (TQ), as the main bioactive substance of Nigella sativa, this systematic review aimed at assessing the therapeutic effects of N.
Mozhdeh Ghamari   +2 more
doaj   +1 more source

HealthWalk: Promoting Health and Mobility through Sensor-Based Rollator Walker Assistance [PDF]

open access: yesarXiv, 2023
Rollator walkers allow people with physical limitations to increase their mobility and give them the confidence and independence to participate in society for longer. However, rollator walker users often have poor posture, leading to further health problems and, in the worst case, falls.
arxiv  

Multimodal optical diagnostics of the microhaemodynamics in upper and lower limbs [PDF]

open access: yes, 2019
The introduction of optical non-invasive diagnostic methods into clinical practice can substantially advance in the detection of early microcirculatory disorders in patients with different diseases.
Dremin, Viktor V.   +7 more
core   +3 more sources

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