Results 31 to 40 of about 268,778 (321)
c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. [PDF]
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are activated by environmental stress. JNK is also activated by proinflammatory cytokines, such as TNF and IL-1, and Toll-like receptor ligands ...
Firestein, Gary S, Guma, Monica
core +1 more source
Diseases associated with articular cartilage disintegration or loss are still therapeutically challenging. The traditional treatment approaches only alleviate the symptoms while potentially causing serious side effects. The limited self-renewal potential
Magdalena Strecanska+3 more
doaj +1 more source
HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena+5 more
core +2 more sources
Objective To evaluate the effectiveness of bazedoxifene in preventing bone loss in patients with rheumatoid arthritis (RA) receiving low-dose glucocorticoids (GCs).
Soo-Kyung Cho+6 more
doaj +1 more source
Estimating the burden of rheumatoid arthritis in Africa:A systematic analysis [PDF]
Rheumatoid arthritis (RA) has an estimated worldwide prevalence of 1%. It is one of the leading causes of chronic morbidity in the developed world, but little is known about the disease burden in Africa. RA is often seen as a minor health problem and has
Abdel-Nasser+32 more
core +2 more sources
IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis
Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo+9 more
doaj +1 more source
Background Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed
Kristine Røren Nordén+10 more
doaj +1 more source
Role of Nigella sativa in the Management of Osteoarthritis: A Systematic Review
Because of the anti-inflammatory properties of thymoquinone (TQ), as the main bioactive substance of Nigella sativa, this systematic review aimed at assessing the therapeutic effects of N.
Mozhdeh Ghamari+2 more
doaj +1 more source
HealthWalk: Promoting Health and Mobility through Sensor-Based Rollator Walker Assistance [PDF]
Rollator walkers allow people with physical limitations to increase their mobility and give them the confidence and independence to participate in society for longer. However, rollator walker users often have poor posture, leading to further health problems and, in the worst case, falls.
arxiv
Multimodal optical diagnostics of the microhaemodynamics in upper and lower limbs [PDF]
The introduction of optical non-invasive diagnostic methods into clinical practice can substantially advance in the detection of early microcirculatory disorders in patients with different diseases.
Dremin, Viktor V.+7 more
core +3 more sources