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Rheumatoid arthritis [PDF]

open access: yesThe Lancet, 2016
Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor outcomes such as high disease activity, presence of autoantibodies, and early joint damage. Treatment
Smolen, Josef S.   +2 more
openaire   +3 more sources

Rheumatoid Arthritis [PDF]

open access: yesAnnals of Internal Medicine, 2019
Rheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease characterized by painful, swollen joints that can severely impair physical function and quality of life. The presenting symptoms of musculoskeletal pain, swelling, and stiffness are common in clinical practice, so familiarity with diagnosing and managing RA is crucial ...
Paola D’Aprile, Alfredo Tarantino
semanticscholar   +5 more sources

Rheumatoid arthritis [PDF]

open access: yesInflammation and Regeneration, 2020
AbstractRheumatoid arthritis is an autoimmune inflammatory disease primarily characterized by synovitis which is accompanied by extra-articular organ involvement, such as interstitial pneumonia, in addition to clinical symptoms including pain, swelling, stiffness of multiple joints, fever, and malaise. Joint destruction progresses soon after the onset,
Primdahl, Jette, Esbensen, Bente Appel
openaire   +5 more sources

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Increases in lipid levels and cancers with tofacitinib prompted a trial of major adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis receiving tofacitinib as compared with a tumor necrosis factor (TNF ...
S. Ytterberg   +12 more
semanticscholar   +1 more source

Angiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis

open access: yesExperimental and Molecular Medicine, 2023
Spondyloarthritis (SpA) is a chronic inflammatory disease that results in bone ankylosis. The tissue renin-angiotensin system (RAS) is an emerging pathway potentially implicated in SpA-associated bone changes.
Jin Sun Choi   +9 more
doaj   +1 more source

The association between comorbidities and disease activity in patients with rheumatoid arthritis: a multicenter, cross-sectional cohort study in Japan with the highest proportion of elderly individuals

open access: yesEgyptian Rheumatology and Rehabilitation, 2022
Background This study aimed to assess the association of disease activity with the presence of comorbidities in patients with rheumatoid arthritis, using the Akita Orthopedic Group on Rheumatoid Arthritis (AORA) registry, a multicenter, cross-sectional ...
Takanori Miura   +5 more
doaj   +1 more source

Post-operative Physical Performance Factors Associated With Gait Speed in Patients Surgically Treated for Hip Fracture: A Cross-Sectional Study [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2019
Objective To determine post-operative physical performance factors associated with gait speed in patients surgically treated for hip fracture. Methods Cross-sectional data from 59 patients (16 males and 43 females; mean age, 79.2±9.1 years) who underwent
Young Tae Jeon   +7 more
doaj   +1 more source

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

open access: yesArthritis & Rheumatology, 2021
To develop updated guidelines for the pharmacologic management of rheumatoid arthritis.
L. Fraenkel   +36 more
semanticscholar   +1 more source

Physical Performance Correlates with Self-Reported Physical Function and Quality of Life in Patients at 3 Months after Total Knee Arthroplasty [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2020
Background Although total knee arthroplasty (TKA) is an effective treatment for knee osteoarthritis, assessment of postoperative outcomes remains unclear.
Jun Hwan Choi   +6 more
doaj   +1 more source

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