Results 171 to 180 of about 433,122 (304)

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Rheumatoid Arthritis: Biomarkers and the Latest Breakthroughs. [PDF]

Int J Mol Sci
Xue M, Wang H, Campos F, Jackson CJ, March L.   +4 more
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Precision and contextualization in claims-based disease activity assessment for systemic lupus erythematosus in Korean populations

Journal of Rheumatic Diseases
Seung Cheol Shim
doaj   +1 more source

Citrullinated peptides as drug candidates for rheumatoid arthritis. [PDF]

Front Immunol
Bustos AH, Brüner M, Kragstrup TW, Astakhova K.   +3 more
europepmc   +1 more source

Rheumatoid Arthritis [PDF]

BMJ, 1938
openaire   +2 more sources

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Seronegative Rheumatoid Arthritis: A Distinct Immunopathological Entity with Erosive Potential. [PDF]

Med Sci (Basel)
Lhotellerie F, Ben Ismail AE, Sarrand J, Soyfoo M.   +3 more
europepmc   +1 more source