Results 191 to 200 of about 433,122 (304)

Temporomandibular Disorders in Patients with Rheumatoid Arthritis. [PDF]

J Clin Med
Wydra-Karbarz A, Guzera Z, Batko B, Moskal M, Błochowiak K.   +4 more
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

CAR T Cell Therapy for Rheumatoid Arthritis. [PDF]

Clin Rev Allergy Immunol
Freeley M.
europepmc   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Associations Between Smartphone-Derived Behavioral Data and Rheumatoid Arthritis Flares. [PDF]

ACR Open Rheumatol
Mollard E, Pedro S, Michaud K.
europepmc   +1 more source

Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis.

, 2018
Sandra Pérez Baos, Juan I. Barrasa, Paula Gratal, Ane Larrañaga Vera, Iván Prieto Potin, Gabriel Herrero Beaumont, Raquel Largo, Juan I. Barrasa   +7 more
openalex   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Differences in Cause-Specific Mortality in Patients With Rheumatoid Arthritis by Sex and Seropositivity. [PDF]

J Rheumatol
Joerns EK, Lopez-Ruiz A, Lennon RJ, Crowson CS, George RJ, Kronzer VL, Davis JM, Myasoedova E.   +7 more
europepmc   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

High Prevalence of Cold Intolerance in Rheumatoid Arthritis: A Case-Control Study. [PDF]

Clin Case Rep
Soroush M, Farzaneh R, Babapour E, Jabbaripour Sarmadian A, Rassouli S, Hassanzadeh Behrouz G, Naseri A, Mahmoudi M, Esalatmanesh K, Malek Mahdavi A, Khabbazi A.   +10 more
europepmc   +1 more source