Results 221 to 230 of about 433,122 (304)

A Short Report on Prescription Monitoring in the Therapeutic Context of Rheumatoid Arthritis at an Italian Local Health Authority [PDF]

Andrea Zovi, Roberto Langella, Francesco Ferrara   +2 more
openalex   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Programmable ROS modulation by nanomedicine for rheumatoid arthritis treatment. [PDF]

Mater Today Bio
Pan G, Zhang Y, Liu D, Wang Y, Zhang H, Pan H, Hou Q, Kong X, Lv F, Xiao N, Zhang R.   +10 more
europepmc   +1 more source

Autologous stem cell transplantation in rheumatoid arthritis

, 2001
John A. Snowden, John J. Moore, Passweg, Paul Cannell, Jacob M. van Laar, Sarah Bingham, Richard K. Burt, P. Emery, S Pavletics, B McKendry, RM Lowenthal, Patrick Durez, A Tyndall   +12 more
openalex  

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

Advanced Science, EarlyView.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang, Biyu Rui, Xuecheng He, Jiajun Wang, Xiangdong Wu, Rui Shao, Xue Meng, Xiaochun Peng, Hengfeng Yuan   +8 more
wiley   +1 more source

Understanding physical activity participation in people living with rheumatoid arthritis. [PDF]

Rheumatol Adv Pract
New-Tolley J, Dyer KA, Lester S, Stanhope J, Burnet S, Ting K, Basnayake S, Murthy S, Hoon E, Proudman S, Hill CL.   +10 more
europepmc   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Ozoralizumab-Induced Multifocal Demyelinating Neuropathy in a Patient With Rheumatoid Arthritis. [PDF]

Cureus
Ikegawa Y, Hamada Y, Hayakawa N, Nishinaka K.   +3 more
europepmc   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source

Development and validation of the manual disease activity score (MDAS) for rheumatoid arthritis. [PDF]

Rheumatol Immunol Res
Salim B, Nasim A, Jahan S, Perveen S, Samreen S, Gul H, Afzal A, Rizwan NUA, Ahmed M, Yasmin S.   +9 more
europepmc   +1 more source