Results 21 to 30 of about 398,619 (213)
Arthritis Research & Therapy, 2017 Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho +4 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2021 Background To evaluate the effect of treatment on serum bone biomarkers and explore whether serum bone biomarkers are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with abatacept.
Shin-ya Kawashiri +24 more
doaj +1 more source
Pain pathogenesis in rheumatoid arthritis -- what have we learned from animal models [PDF]
PAIN 2018 Sep; 159 Suppl:S98-S109, 2019 Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint inflammation and joint pain. Much of RA treatment is focused on suppressing inflammation, with the idea being that if inflammation is controlled other symptoms, such as pain, will disappear. However, pain is the most common complaint of RA patients, is often still present
arxiv +1 more source
A Sub-pixel Accurate Quantification of Joint Space Narrowing Progression in Rheumatoid Arthritis [PDF]
, 2022 Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects peripheral synovial joints, like fingers, wrist and feet. Radiology plays a critical role in the diagnosis and monitoring of RA. Limited by the current spatial resolution of radiographic imaging, joint space narrowing (JSN) progression of RA with the same reason above can ...
arxiv +1 more source
Infectious Agents and Cancer, 2023 Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen +8 more
doaj +1 more source
Autoimmunity, 2017 To investigate the expression patterns of activation-induced cytidine deaminase (AID) variants in peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (AS) and examine their clinical implications, we isolated PBMCs from ...
Ji-Young Kim +4 more
doaj +1 more source
Rheumatoid Arthritis: Automated Scoring of Radiographic Joint Damage [PDF]
arXiv, 2021 Rheumatoid arthritis is an autoimmune disease that causes joint damage due to inflammation in the soft tissue lining the joints known as the synovium. It is vital to identify joint damage as soon as possible to provide necessary treatment early and prevent further damage to the bone structures.
arxiv
A Deep Registration Method for Accurate Quantification of Joint Space Narrowing Progression in Rheumatoid Arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that results in progressive articular destruction and severe disability. Joint space narrowing (JSN) progression has been regarded as an important indicator for RA progression and has received sustained attention. In the diagnosis and monitoring of RA, radiology plays a crucial role
arxiv +1 more source
β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function
Frontiers in Immunology, 2017 Emerging evidence suggests that the β2 integrin family of adhesion molecules have an important role in suppressing immune activation and inflammation.
Leonie Schittenhelm +6 more
doaj +1 more source
NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease
Acta Biochimica et Biophysica Sinica, 2022 The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the ...
Guan Yanling +8 more
doaj +1 more source