Results 41 to 50 of about 1,164,546 (387)

IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway

Infectious Agents and Cancer, 2023
Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen, Yu Zhang, Pingping Zhang, Mengzhu Wei, Tian Tian, Yanling Guan, Chenchen Han, Wei Wei, Yang Ma   +8 more
doaj   +1 more source

An introduction to the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas [PDF]

, 2005
This article gives a short overview of the development and characteristics of the OMERACT rheumatoid arthritis MRI scoring system (RAMRIS), followed by an introduction to the use of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas.
Bird, P., Conaghan, P., Edmonds, J., Ejbjerg, B., Emery, P., Genant, H., Lassere, M., McQueen, F., Peterfy, C., Østergaard, M.   +9 more
core   +2 more sources

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

Arthritis care & research, 2016
To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid arthritis (RA).
J. Singh, K. Saag, S. L. Bridges, E. Akl, Raveendhara R. Bannuru, M. Sullivan, E. Vaysbrot, Christine McNaughton, M. Osani, R. Shmerling, J. Curtis, D. Furst, D. Parks, A. Kavanaugh, J. O'dell, Charles King, Amye Leong, E. Matteson, J. Schousboe, B. Drevlow, S. Ginsberg, J. Grober, E. St.clair, E. Tindall, Amy S. Miller, T. McAlindon   +25 more
semanticscholar   +1 more source

β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function

Frontiers in Immunology, 2017
Emerging evidence suggests that the β2 integrin family of adhesion molecules have an important role in suppressing immune activation and inflammation.
Leonie Schittenhelm, Leonie Schittenhelm, Leonie Schittenhelm, Catharien M. Hilkens, Catharien M. Hilkens, Vicky L. Morrison, Vicky L. Morrison   +6 more
doaj   +1 more source

NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease

Acta Biochimica et Biophysica Sinica, 2022
The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the ...
Guan Yanling, Gu Yiyue, Li Hao, Liang Bo, Han Chenchen, Zhang Yu, Liu Qian, Wei Wei, Ma Yang   +8 more
doaj   +1 more source

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

Annals of the Rheumatic Diseases, 2010
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear and consensual international recommendations on RA treatment are not available.
J. Smolen, R. Landewé, F. Breedveld, M. Dougados, P. Emery, C. Gaujoux-Viala, S. Gorter, R. Knevel, J. Nam, M. Schoels, D. Aletaha, M. Buch, L. Gossec, T. Huizinga, J. Bijlsma, G. Burmester, B. Combe, M. Cutolo, C. Gabay, J. Gómez-Reino, M. Kouloumas, T. Kvien, E. Martı́n-Mola, I. McInnes, K. Pavelka, P. V. van Riel, Marieke Scholte, D. Scott, T. Sokka, G. Valesini, R. V. van Vollenhoven, K. Winthrop, J. Wong, A. Zink, D. M. van der Heijde   +34 more
semanticscholar   +1 more source

DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis [PDF]

, 2005
The Disease Activity Score using 28 joint counts (DAS28) has been developed in a cohort of patients with rheumatoid arthritis in which only conventional anti-rheumatic treatments were used. It has extensively been validated to monitor disease activity in
Fransen, Jaap, van Riel, Piet LCM
core   +2 more sources

Establishment of a qualified integrated care system after total knee arthroplasty as a role of regional rheumatoid and degenerative arthritis centers

BMC Geriatrics, 2022
Background The geriatric population and advanced knee osteoarthritis are rapidly increasing in Korea, and the socioeconomic burden of total knee arthroplasty (TKA) is increasing.
Eun Young Han, Sang Rim Kim, Kye Hee Cho, Sang Hee Im   +3 more
doaj   +1 more source

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Al-Riyami, Benderdour, Chu, Collins, Conti, Cooke, Fang, Feng, Goodridge, Goodridge, Goodridge, Gulen, Harnett, Harrington, Ito, Ivanov, Kelchtermans, Kenny, Koenders, Koshy, Kulkarni, Langrish, Lubberts, Marshall, Martin, McInnes, Murugaiyan, Nakae, Naor, Niedbala, Petermann, Pickens, Price, Reynolds, Roark, Sato, Shahrara, Shibata, Staschke, Sutton, Szanto, Takayanagi, Tanaka, Vermeire, Whelan, Xu, Xu, Yago   +47 more
core   +1 more source

‘The current mental health status of children and young people with JIA, and their wider family’: a charity partner collaboration survey

Pediatric Rheumatology Online Journal, 2023
Background This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of the United Kingdom (UK).
Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley, J. Clinch   +7 more
doaj   +1 more source