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Pain pathogenesis in rheumatoid arthritis -- what have we learned from animal models [PDF]

PAIN 2018 Sep; 159 Suppl:S98-S109, 2019
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint inflammation and joint pain. Much of RA treatment is focused on suppressing inflammation, with the idea being that if inflammation is controlled other symptoms, such as pain, will disappear. However, pain is the most common complaint of RA patients, is often still present
arxiv   +1 more source

A Sub-pixel Accurate Quantification of Joint Space Narrowing Progression in Rheumatoid Arthritis [PDF]

, 2022
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects peripheral synovial joints, like fingers, wrist and feet. Radiology plays a critical role in the diagnosis and monitoring of RA. Limited by the current spatial resolution of radiographic imaging, joint space narrowing (JSN) progression of RA with the same reason above can ...
arxiv   +1 more source

The risk of malignancy and its incidence in early rheumatoid arthritis patients treated with biologic DMARDs

Arthritis Research & Therapy, 2017
Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho, Jiyoung Lee, Minkyung Han, Sang-Cheol Bae, Yoon-Kyoung Sung   +4 more
doaj   +1 more source

Association between serum bone biomarker levels and therapeutic response to abatacept in patients with rheumatoid arthritis (RA): a multicenter, prospective, and observational RA ultrasound cohort study in Japan

BMC Musculoskeletal Disorders, 2021
Background To evaluate the effect of treatment on serum bone biomarkers and explore whether serum bone biomarkers are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with abatacept.
Shin-ya Kawashiri, Yushiro Endo, Ayako Nishino, Momoko Okamoto, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Toshiyuki Aramaki, Yukitaka Ueki, Tamami Yoshitama, Nobutaka Eiraku, Naoki Matsuoka, Akitomo Okada, Keita Fujikawa, Hiroaki Hamada, Shuji Nagano, Yoshifumi Tada, Atsushi Kawakami   +24 more
doaj   +1 more source

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

Arthritis care & research, 2016
To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid arthritis (RA).
J. Singh, K. Saag, S. L. Bridges, E. Akl, Raveendhara R. Bannuru, M. Sullivan, E. Vaysbrot, Christine McNaughton, M. Osani, R. Shmerling, J. Curtis, D. Furst, D. Parks, A. Kavanaugh, J. O'dell, Charles King, Amye Leong, E. Matteson, J. Schousboe, B. Drevlow, S. Ginsberg, J. Grober, E. St.clair, E. Tindall, Amy S. Miller, T. McAlindon   +25 more
semanticscholar   +1 more source

Change in bone mineral density in post menopausal women with rheumatoid arthritis [PDF]

, 2013
Introduction: Low bone mass is a serious complication of post menopausal women with rheumatoid arthritis. We determined the Change in Bone Mineral Density in postmenopausal women with rheumatoid arthritis.
Aghaei, M., Aili, A., Jamshir, M., Khani, S.H., Mohebi, E.G., Pour, N.B., Sedighi, S., Shirashiani, M., Shojaa, M., Zayeni, H.   +9 more
core   +1 more source

RHEUMATOID ARTHRITIS [PDF]

BMJ, 1913
n ...
openaire   +3 more sources

IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway

Infectious Agents and Cancer, 2023
Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen, Yu Zhang, Pingping Zhang, Mengzhu Wei, Tian Tian, Yanling Guan, Chenchen Han, Wei Wei, Yang Ma   +8 more
doaj   +1 more source

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

Annals of the Rheumatic Diseases, 2010
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear and consensual international recommendations on RA treatment are not available.
J. Smolen, R. Landewé, F. Breedveld, M. Dougados, P. Emery, C. Gaujoux-Viala, S. Gorter, R. Knevel, J. Nam, M. Schoels, D. Aletaha, M. Buch, L. Gossec, T. Huizinga, J. Bijlsma, G. Burmester, B. Combe, M. Cutolo, C. Gabay, J. Gómez-Reino, M. Kouloumas, T. Kvien, E. Martı́n-Mola, I. McInnes, K. Pavelka, P. V. van Riel, Marieke Scholte, D. Scott, T. Sokka, G. Valesini, R. V. van Vollenhoven, K. Winthrop, J. Wong, A. Zink, D. M. van der Heijde   +34 more
semanticscholar   +1 more source

Rheumatoid Arthritis: Automated Scoring of Radiographic Joint Damage [PDF]

arXiv, 2021
Rheumatoid arthritis is an autoimmune disease that causes joint damage due to inflammation in the soft tissue lining the joints known as the synovium. It is vital to identify joint damage as soon as possible to provide necessary treatment early and prevent further damage to the bone structures.
arxiv