Isolation of rheumatoid factors [PDF]
AbstractA method for the separation of rheumatoid factors into two serologically distinct macroglobulins is described. Macroglobulins, reacting with cells coated with human as well as with rabbit gamma globulin, were found to be mainly 19.4S, but occasionally such preparations contained minor constituents sedimenting at 22s as well as 27s ...
Edith R. Schwartz, Ralph Heimer
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Protein concentration of synovial fluid in chronic rheumatoid arthritis. Estimation of protein in the synovial fluid of chronic rheumatoid arthritis by gel filtration and paper electrophoresis [PDF]
For the purpose to reveal the characteris6cs of the synovial fluid of the chronic rheumatoid arthritis the proteins of the synovial fluid and blood serum have been analysed by employing the methods of electrophoresis, gel filtration on Sephadex G-200 ...
Seno, Takashi
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Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. [PDF]
OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical ...
Barcellos, Lisa F+13 more
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Adverse reactions of biological therapies in patients with psoriasis [PDF]
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R.+5 more
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Effect of Etanercept on anti-carbamylated protein antibodies in patients with rheumatoid arthritis [PDF]
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e.
Alessandri, Cristiano+4 more
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TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele+11 more
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Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan+115 more
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Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis:Results from the Norfolk Arthritis Register [PDF]
Objectives: Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of this study was to investigate their association with long-term outcomes of disability
Aletaha+36 more
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Radioimmunoassay of rheumatoid factor [PDF]
AbstractA radioimmunological method for assaying rheumatoid factor is proposed and analyzed. The method is based on the reaction between rheumatoid factor, either purified or present in serum, and purified labeled yg globulin. This assay permits a quantitative estimation of rheumatoid factor levels in rheumatoid‐positive serum and provides evidence ...
S. Suteanu, Paul Franchimont
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Optimising use of electronic health records to describe the presentation of rheumatoid arthritis in primary care: a strategy for developing code lists [PDF]
Background Research using electronic health records (EHRs) relies heavily on coded clinical data. Due to variation in coding practices, it can be difficult to aggregate the codes for a condition in order to define cases.
A Hansell+37 more
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