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Rheumatoid factor: study history and concept evolution
Rheumatoid factor became the first laboratory marker of rheumatoid arthritis and one of the first serological markers used to recognize the major autoimmune diseases. Details of the discovery with special regard to contribution of E. Waaler and H.
Sergei V. Guliaev+2 more
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The Effect of Smoking on Disease Activity in Rheumatoid Arthritis – Our Experience
The aim of this study was to investigate the association of smoking with disease activity, seropositivity, age and gender in patients with rheumatoid arthritis. We included 89 rheumatoid arthritis patients.
Ana Gudelj Gračanin+5 more
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RHEUMATOID FACTOR AND THE PATHOGENESIS OF RHEUMATOID ARTHRITIS [PDF]
In analogy with the two categories of reactants which are used in the serological tests for the unusual category of macroglobulins called rheumatoid factor, two fluorescent reactants have been prepared for the detection of rheumatoid factor in situ in tissue sections: fluorescent antigen-rabbit antibody (immune) complex, in the present study, and ...
Adam Nowoslawski+3 more
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Subclinical features of atherosclerotic remodeling of arteries in patients with rheumatoid arthritis
The aim of the research – to study the structural-functional state of artery walls in patients with rheumatoid arthritis depending of disease duration, seropositivity for rheumatoid factor/ cyclic citrullinated peptide antibodies, disease activity ...
I. M. Fushtei+3 more
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Objectives: H. pylori infection has been associated with some autoimmune disorders. The aim of this study was to evaluate the serum concentrations of rheumatoid factor and anti-nuclear antibodies in H. pylori-infected peptic ulcer patients, H.
Abdollah Jafarzadeh+4 more
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Multiplicity of rheumatoid factor [PDF]
AbstractThe reactions between rheumatoid factor and erythrocytes sensitized by antibodies of human, rabbit and guinea pig origin were studied using absorption, elution, dispersion, inhibition and mixed agglutination experiments. The results indicated that there are separate molecules of the rheumatoid factor combining with γ‐globulin of the three ...
Olav Tonder, Felix Milgrom
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Effect of Rheumatoid Factor on Vascular Stiffness in General Population without Joint Symptoms [PDF]
ObjectivesThe role of rheumatoid factor (RF) in vascular stiffness and cardiovascular risk in subjects without joint symptoms remains unclear. We investigated vascular stiffness in subjects without joint symptoms using pulse wave velocity (PWV ...
Ji Hyun Lee+6 more
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Prevalence and predictive factors of difficult-to-treat rheumatoid arthritis: the KURAMA cohort
Difficult-to-treat rheumatoid arthritis (D2T RA) is a multifactorial condition in which disease activity of RA persists despite consecutive treatment with biological or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs).
Ryu Watanabe+7 more
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Isolation of rheumatoid factors [PDF]
AbstractA method for the separation of rheumatoid factors into two serologically distinct macroglobulins is described. Macroglobulins, reacting with cells coated with human as well as with rabbit gamma globulin, were found to be mainly 19.4S, but occasionally such preparations contained minor constituents sedimenting at 22s as well as 27s ...
Edith R. Schwartz, Ralph Heimer
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Background: Rheumatoid arthritis (RA) is an autoimmune disease, which mistakenly attacks the joints and induces the inflammatory changes that thicken the joints (the synovium) resulting in swelling and pain in and around the joints. It causes pain, joint
Bharat Kumar+2 more
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