Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]
Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano+16 more
core +1 more source
Subclinical features of atherosclerotic remodeling of arteries in patients with rheumatoid arthritis
The aim of the research – to study the structural-functional state of artery walls in patients with rheumatoid arthritis depending of disease duration, seropositivity for rheumatoid factor/ cyclic citrullinated peptide antibodies, disease activity ...
I. M. Fushtei+3 more
doaj +1 more source
Pathogenetic insights from the treatment of rheumatoid arthritis [PDF]
Rheumatoid arthritis is a chronic autoimmune disease that causes progressive articular damage, functional loss, and comorbidity. The development of effective biologics and small-molecule kinase inhibitors in the past two decades has substantially ...
McInnes, Iain B., Schett, Georg
core +1 more source
Analysis of gut microbiota in rheumatoid arthritis patients. Disease-related dysbiosis and modifications induced by etanercept [PDF]
A certain number of studies were carried out to address the question of how dysbiosis could affect the onset and development of rheumatoid arthritis (RA), but little is known about the reciprocal influence between microbiota composition and ...
D'Amelio, R+11 more
core +1 more source
Objectives: H. pylori infection has been associated with some autoimmune disorders. The aim of this study was to evaluate the serum concentrations of rheumatoid factor and anti-nuclear antibodies in H. pylori-infected peptic ulcer patients, H.
Abdollah Jafarzadeh+4 more
doaj +1 more source
Bridging disconnected networks of first and second lines of biologic therapies in rheumatoid arthritis with registry data: Bayesian evidence synthesis with target trial emulation [PDF]
Objective: We aim to utilise real world data in evidence synthesis to optimise an evidence base for the effectiveness of biologic therapies in rheumatoid arthritis in order to allow for evidence on first-line therapies to inform second-line effectiveness estimates.
arxiv +1 more source
Multiplicity of rheumatoid factor [PDF]
AbstractThe reactions between rheumatoid factor and erythrocytes sensitized by antibodies of human, rabbit and guinea pig origin were studied using absorption, elution, dispersion, inhibition and mixed agglutination experiments. The results indicated that there are separate molecules of the rheumatoid factor combining with γ‐globulin of the three ...
Olav Tonder, Felix Milgrom
openaire +3 more sources
Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimrnune disease [PDF]
A20 [also known as TNFAIP3 (tumour necrosis factor a-induced protein 3)] restricts and terminates inflammatory responses through modulation of the ubiquitination status of central components in NF-kappa B (nuclear factor kappa B), IRF3 (interferon ...
Beyaert, Rudi+2 more
core +2 more sources
Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi+8 more
wiley +1 more source
Pain pathogenesis in rheumatoid arthritis -- what have we learned from animal models [PDF]
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint inflammation and joint pain. Much of RA treatment is focused on suppressing inflammation, with the idea being that if inflammation is controlled other symptoms, such as pain, will disappear. However, pain is the most common complaint of RA patients, is often still present
arxiv +1 more source