Results 31 to 40 of about 14,745,234 (347)
The Effect of Smoking on Disease Activity in Rheumatoid Arthritis – Our Experience
Acta Clinica Croatica, 2020 The aim of this study was to investigate the association of smoking with disease activity, seropositivity, age and gender in patients with rheumatoid arthritis. We included 89 rheumatoid arthritis patients.
Ana Gudelj Gračanin +5 more
doaj +1 more source
Научно-практическая ревматология, 2022 Objective. Inflammation in rheumatoid arthritis (RA) leads to the development of local and generalized bone loss. Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibodies (ACCP) are believed to play a negative role in the radiological ...
P. S. Kovalenko +3 more
doaj +1 more source
Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]
, 2016 Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano +16 more
core +1 more source
Arthritis & Rheumatology, 2019 Anti–citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are commonly present in rheumatoid arthritis (RA) without a clear rationale for their coexistence. Moreover, autoantibodies develop against proteins with different posttranslational
Zihao Zheng +8 more
semanticscholar +1 more source
Subclinical features of atherosclerotic remodeling of arteries in patients with rheumatoid arthritis
Patologìâ, 2019 The aim of the research – to study the structural-functional state of artery walls in patients with rheumatoid arthritis depending of disease duration, seropositivity for rheumatoid factor/ cyclic citrullinated peptide antibodies, disease activity ...
I. M. Fushtei +3 more
doaj +1 more source
Synovial tissue macrophages: friend or foe? [PDF]
, 2017 Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Alivernini, Stefano +1 more
core +2 more sources
Immunoglobulin G structure and rheumatoid factor epitopes
PLoS ONE, 2019 Antibodies are important for immunity and exist in several classes (IgM, IgD, IgA, IgG, IgE). They are composed of symmetric dimeric molecules with two antigen binding regions (Fab) and a constant part (Fc), usually depicted as Y-shaped molecules ...
S. Maibom-Thomsen +8 more
semanticscholar +1 more source
Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]
, 2018 Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan +44 more
core +1 more source
Arthritis & Rheumatology, 2018 In rheumatoid arthritis (RA), anti–citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are commonly used to aid in the diagnosis. Although these autoantibodies are mainly found in RA, their specificity is not optimal.
M. Verheul +17 more
semanticscholar +1 more source
Arthritis & Rheumatology, 2018 Juvenile idiopathic arthritis (JIA) comprises 7 heterogeneous categories of chronic childhood arthritides. Approximately 5% of children with JIA have rheumatoid factor (RF)–positive arthritis, which phenotypically resembles adult rheumatoid arthritis (RA)
A. Hinks +29 more
semanticscholar +1 more source