Results 221 to 230 of about 448,470 (384)

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin‐10 Antagonism

open access: yesArthritis &Rheumatology, EarlyView.
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes   +14 more
wiley   +1 more source

Oral glucocorticoid patterns use in moderate to severe active SLE: insights from the Spanish SPOCS data. [PDF]

open access: yesLupus Sci Med
Rua-Figueroa I   +16 more
europepmc   +1 more source

American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

open access: yesArthritis care & research, 2012
M. Hochberg   +9 more
semanticscholar   +1 more source

Clinical Images: Acute vision loss due to granulomatosis with polyangiitis

open access: yes
Arthritis &Rheumatology, EarlyView.
Hirotaka Yamamoto, Yoshinori Taniguchi
wiley   +1 more source

Gout and NLRP3 Inflammasome Biology

open access: yesArthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Correction: Pulmonary arteritis in the course of granulomatosis with polyangiitis. [PDF]

open access: yesRheumatol Int
Sobuń A   +5 more
europepmc   +1 more source

Innate Lymphoid Cell Phenotypic and Functional Alterations in Patients With Systemic Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood disease classically attributed to innate immune cell dysregulation. This study aimed to elucidate the role of innate lymphoid cells (ILCs), including natural killer (NK) cells and helper‐ILCs (hILCs), in sJIA during clinically inactive disease (CID) through phenotypic and ...
Linda Quatrini   +19 more
wiley   +1 more source

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