Results 1 to 10 of about 1,501 (80)

Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Rhinovirus causes many types of respiratory illnesses, ranging from minor colds to exacerbations of asthma. Moraxella catarrhalis is an opportunistic pathogen that is increased in abundance during rhinovirus illnesses and asthma exacerbations and is ...
Eishika Dissanayake   +11 more
doaj   +1 more source

Combining CD34+ stem cell selection with prophylactic pathogen and leukemia directed T‐cell immunotherapy to simultaneously reduce graft versus host disease, infection, and leukemia recurrence after allogeneic stem cell transplant

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 159-165, January 2023., 2023
Donor stem cell product undergoes CD34 stem cell selection. CD34 positive stem cells are used for transplantation. Pathogen‐ and leukemia‐specific T‐cells are manufactured from CD34 negative fraction and infused prophylactically 21 days after transplant.
David J. Gottlieb   +12 more
wiley   +1 more source

Viruses in sanctuary chimpanzees across Africa

open access: yesAmerican Journal of Primatology, Volume 85, Issue 1, January 2023., 2023
Abstract Infectious disease is a major concern for both wild and captive primate populations. Primate sanctuaries in Africa provide critical protection to thousands of wild‐born, orphan primates confiscated from the bushmeat and pet trades. However, uncertainty about the infectious agents these individuals potentially harbor has important implications ...
Emily Dunay   +9 more
wiley   +1 more source

Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype. [PDF]

open access: yesPLoS ONE, 2018
Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Rhinovirus, which causes acute exacerbations may also accelerate progression of lung disease in these patients.
Mohammad Farazuddin   +5 more
doaj   +1 more source

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations. [PDF]

open access: yesPLoS Pathogens, 2011
Rhinovirus infections are the major cause of asthma exacerbations. We hypothesised that IL-15, a cytokine implicated in innate and acquired antiviral immunity, may be deficient in asthma and important in the pathogenesis of asthma exacerbations.
Vasile Laza-Stanca   +9 more
doaj   +1 more source

Secondary infections worsen the outcome of COVID‐19 in patients with hematological malignancies: A report from the ITA‐HEMA‐COV

open access: yesHematological Oncology, Volume 40, Issue 5, Page 846-856, December 2022., 2022
Abstract The impact of secondary infections (SI) on COVID‐19 outcome in patients with hematological malignancies (HM) is scarcely documented. To evaluate incidence, clinical characteristics, and outcome of SI, we analyzed the microbiologically documented SI in a large multicenter cohort of adult HM patients with COVID‐19.
Patrizia Zappasodi   +54 more
wiley   +1 more source

Engineering the common cold to be a live-attenuated SARS-CoV-2 vaccine

open access: yesFrontiers in Immunology, 2022
According to the American Centers for Disease Control and Prevention, people in all age groups catch two or more “colds” per year, at least half of which are caused by human rhinoviruses.
Laura M. Kasman
doaj   +1 more source

Rapid on‐site molecular Point of Care Testing during influenza outbreaks in aged care facilities improves antiviral use and reduces hospitalisation

open access: yesAustralian and New Zealand Journal of Public Health, Volume 46, Issue 6, Page 884-888, December 2022., 2022
Abstract Objective: Western Sydney Local Health District (WSLHD) measured the utility and validity of rapid molecular point‐of‐care testing (POCT) in aged care facilities (ACFs) experiencing influenza‐like illness (ILI) outbreaks against routine laboratory testing.
Elizabeth Escarate   +9 more
wiley   +1 more source

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. [PDF]

open access: yesPLoS Pathogens, 2010
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial ...
Louise Slater   +14 more
doaj   +1 more source

Rhinovirus species and tonsillar immune responses

open access: yesClinical and Translational Allergy, 2019
Background Rhinovirus A and C infections are important contributors to asthma induction and exacerbations. No data exist on the interaction of local immune responses in rhinovirus infection. Therefore, we aimed to determine the tonsillar immune responses
Emilia Mikola   +11 more
doaj   +1 more source

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