Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype. [PDF]
PLoS ONE, 2018 Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Rhinovirus, which causes acute exacerbations may also accelerate progression of lung disease in these patients.
Mohammad Farazuddin +5 more
doaj +2 more sources
Allergology International, 2004 Rhinoviruses cause the majority of common colds, which often provoke wheezing in patients with asthma. The precise mechanisms responsible for the rhinovirus infection-induced exacerbations of bronchial asthma remain uncertain.
Mutsuo Yamaya, Hidetada Sasaki
doaj +3 more sources
Recent advances in understanding rhinovirus immunity [version 1; referees: 4 approved]
F1000Research, 2018 Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in ...
Spyridon Makris, Sebastian Johnston
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Exploring the Clinical Characteristics and Outcomes of Rhinovirus Infection in Hospitalized Children Compared with Other Respiratory Viruses [PDF]
ChildrenBackground: Acute viral respiratory tract infections constitute a significant challenge in pediatric healthcare globally, with rhinovirus representing one of the primary etiological agents.
Sigrid Covaci +2 more
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Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium
Frontiers in Cellular and Infection Microbiology, 2023 Rhinovirus causes many types of respiratory illnesses, ranging from minor colds to exacerbations of asthma. Moraxella catarrhalis is an opportunistic pathogen that is increased in abundance during rhinovirus illnesses and asthma exacerbations and is ...
Eishika Dissanayake +11 more
doaj +1 more source
Engineering the common cold to be a live-attenuated SARS-CoV-2 vaccine
Frontiers in Immunology, 2022 According to the American Centers for Disease Control and Prevention, people in all age groups catch two or more “colds” per year, at least half of which are caused by human rhinoviruses.
Laura M. Kasman
doaj +1 more source
Rhinovirus species and tonsillar immune responses
Clinical and Translational Allergy, 2019 Background Rhinovirus A and C infections are important contributors to asthma induction and exacerbations. No data exist on the interaction of local immune responses in rhinovirus infection. Therefore, we aimed to determine the tonsillar immune responses
Emilia Mikola +11 more
doaj +1 more source
Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
Cells, 2022 Asthma is a chronic airway disease whose exacerbations are often triggered by rhinovirus infection. TGF-β1 induces rhinovirus replication in infected cells.
Susanne Krammer +7 more
doaj +1 more source
The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.
PLoS Pathogens, 2011 Rhinovirus infections are the major cause of asthma exacerbations. We hypothesised that IL-15, a cytokine implicated in innate and acquired antiviral immunity, may be deficient in asthma and important in the pathogenesis of asthma exacerbations.
Vasile Laza-Stanca +9 more
doaj +1 more source
Rhinovirus induces airway remodeling: what are the physiological consequences?
Respiratory Research, 2023 Background Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airway remodeling.
Cassandra Spector +3 more
doaj +1 more source