Results 41 to 50 of about 46,812 (255)
Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication
Nature Communications, 2022 Evidence exists that the typically antiviral signaling mediator STING is, counterintuitively, needed for optimal human rhinovirus infection. Here the authors confirm this finding and show how human rhinovirus can reduce stored Ca2+ levels to drive this ...
Martha Triantafilou +11 more
doaj +1 more source
Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice.
PLoS ONE, 2014 Human rhinovirus is a key viral trigger for asthma exacerbations. To date, murine studies investigating rhinovirus-induced exacerbation of allergic airways disease have employed systemic sensitisation/intranasal challenge with ovalbumin.
Jennifer A Phan +6 more
doaj +1 more source
Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus
EMBO Molecular Medicine, 2012 The importance of NF‐κB activation and deficient anti‐viral interferon induction in the pathogenesis of rhinovirus‐induced asthma exacerbations is poorly understood.
Nathan W. Bartlett +17 more
doaj +1 more source
Population structure and evolution of Rhinoviruses.
PLoS ONE, 2014 Rhinoviruses, formerly known as Human rhinoviruses, are the most common cause of air-borne upper respiratory tract infections in humans. Rhinoviruses belong to the family Picornaviridae and are divided into three species namely, Rhinovirus A, -B and -C ...
Vaishali P Waman +3 more
doaj +1 more source
Pathogenesis of rhinovirus infection [PDF]
Current Opinion in Virology, 2012 Since its discovery in 1956, rhinovirus (RV) has been recognized as the most important virus producing the common cold syndrome. Despite its ubiquity, little is known concerning the pathogenesis of RV infections, and some of the research in this area has led to contradictions regarding the molecular and cellular mechanisms of RV-induced illness.
Joshua L. Kennedy +4 more
openaire +3 more sources
PLoS ONE, 2017 Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is unknown.
Nadine Upton +17 more
doaj +1 more source
Global Pediatric Health, 2023 Acute otitis media (AOM) is one of the most common infectious diseases in pediatric clinical facilities and has a significant impact on health care. It is a polymicrobial disease and is usually preceded by a viral upper respiratory tract infection.
Anton Budhi Darmawan +5 more
doaj +1 more source
Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Rhinovirus (RV) is the causative agent of the common cold and other respiratory tract infections. Despite the vast prevalence, effective treatment or prevention strategies are lacking.
Guido A. Gualdoni +11 more
semanticscholar +1 more source
Frontiers in AllergyRhinovirus is a widespread virus associated with several respiratory diseases, especially asthma exacerbation. Currently, there are no accurate therapies for rhinovirus. Encouragingly, it is found that during rhinovirus-induced immunoreactions the levels
Le Sang +4 more
doaj +1 more source
JAMA pediatrics, 2019 Importance Rhinovirus infection in early life, particularly with allergic sensitization, is associated with higher risks of developing recurrent wheeze and asthma.
K. Hasegawa +9 more
semanticscholar +1 more source