Results 41 to 50 of about 81,443 (260)

Complete Genome Sequence of a Divergent Human Rhinovirus C Isolate from an Infant with Severe Community-Acquired Pneumonia in Colorado, USA. [PDF]

open access: yes, 2017
Here, we report the genome sequence of a divergent human rhinovirus C isolate identified from an infant with a severe community-acquired respiratory infection. RNA sequencing performed on an Illumina platform identified reads aligning to human rhinovirus
DeRisi, Joseph L   +4 more
core   +2 more sources

Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features

open access: yesClinical and Translational Allergy, 2012
Background Human rhinoviruses, major precipitants of asthma exacerbations, induce lower airway inflammation and mediate angiogenesis. The purpose of this study was to assess the possibility that rhinoviruses may also contribute to the fibrotic component ...
Skevaki Chrysanthi L   +13 more
doaj   +1 more source

Bronchiolitis – It Is Time for a Unique Definition [PDF]

open access: yes, 2016
Bronchiolitis is the most common lower respiratory tract infections in infants. It is time to reach a unique clinical definition, encompassing the acute onset of respiratory distress with cough, tachypnoea, retraction and
Midulla, Fabio, Nenna, Raffaella
core   +1 more source

Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19

open access: yesNature Communications, 2023
Rhinoviruses and allergens, such as house dust mite are major agents responsible for asthma exacerbations. The influence of pre-existing airway inflammation on the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely ...
Urszula Radzikowska   +24 more
doaj   +1 more source

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

open access: yes, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora   +22 more
core   +1 more source

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response [PDF]

open access: yes, 2012
Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-?, influences interferon (IFN) production by primary
Amanda Tatler   +10 more
core   +7 more sources

Human rhinovirus detection in the lower respiratory tract of hematopoietic cell transplant recipients: association with mortality

open access: yesHaematologica, 2017
Human rhinoviruses are the most common respiratory viruses detected in patients after hematopoietic cell transplantation. Although rhinovirus appears to occasionally cause severe lower respiratory tract infection in immunocompromised patients, the ...
Sachiko Seo   +11 more
doaj   +1 more source

Additional Rhinovirus Serotypes

open access: yesExperimental Biology and Medicine, 1964
SummaryFifty-two rhinovirus strains were isolated from 672 cases of acute respiratory illness in children and adults and 4 strains were recovered from well controls. Respiratory disease cases among adults which yielded a rhinovirus were nearly all upper respiratory illness (common cold) whereas the cases among children often showed lower respiratory ...
V V, HAMPARIAN   +2 more
openaire   +2 more sources

Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus

open access: yesEMBO Molecular Medicine, 2012
The importance of NF‐κB activation and deficient anti‐viral interferon induction in the pathogenesis of rhinovirus‐induced asthma exacerbations is poorly understood.
Nathan W. Bartlett   +17 more
doaj   +1 more source

Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice.

open access: yesPLoS ONE, 2014
Human rhinovirus is a key viral trigger for asthma exacerbations. To date, murine studies investigating rhinovirus-induced exacerbation of allergic airways disease have employed systemic sensitisation/intranasal challenge with ovalbumin.
Jennifer A Phan   +6 more
doaj   +1 more source

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