Results 61 to 70 of about 46,812 (255)
Arthritis &Rheumatology, Accepted Article.Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens +14 more
wiley +1 more source
Definitions, 2020 . Introduction . Rhinoviruses represent one of the most common respiratory viruses and belong to the Picornoviridae family,
А.Д. Ксенафонтов +9 more
semanticscholar +1 more source
Additional Rhinovirus Serotypes
Experimental Biology and Medicine, 1964 SummaryFifty-two rhinovirus strains were isolated from 672 cases of acute respiratory illness in children and adults and 4 strains were recovered from well controls. Respiratory disease cases among adults which yielded a rhinovirus were nearly all upper respiratory illness (common cold) whereas the cases among children often showed lower respiratory ...
Vincent V. Hamparian +2 more
openaire +3 more sources
Журнал инфектологии, 2020 Purpose. Rhinovirus infection has in the past been perceived as a disease capable of causing mild respiratory symptoms in most cases in children. Modern clinical and epidemiological studies have shown that rhinovirus infection in adults and children and ...
M. A. Bichurina +4 more
doaj +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection
Exploration, EarlyView.Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang +20 more
wiley +1 more source
Rhinovirus Biology, Antigenic Diversity, and Advancements in the Design of a Human Rhinovirus Vaccine [PDF]
Frontiers in Microbiology, 2017 Human rhinovirus (HRV) remains a leading cause of several human diseases including the common cold. Despite considerable research over the last 60 years, development of an effective vaccine to HRV has been viewed by many as unfeasible due, in part, to the antigenic diversity of circulating HRVs in nature.
Christopher C. Stobart +3 more
openaire +3 more sources
eLife, 2021 For an emerging disease like COVID-19, systems immunology tools may quickly identify and quantitatively characterize cells associated with disease progression or clinical response. With repeated sampling, immune monitoring creates a real-time portrait of
Sierra M Barone +7 more
doaj +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Exploration, EarlyView.Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang +6 more
wiley +1 more source
Global Challenges, EarlyView.As population growth, urbanization, and climate change increase the spread of pathogens, hospital infections now affect 1 in 31 patients, costing billions annually. This study presents a new approach by integrating copper and zinc oxide nanoparticles into 3D‐printed materials.
Andrei‐Florin Sandu +2 more
wiley +1 more source