Results 271 to 280 of about 4,436,011 (309)
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Rho Transcription Factor: Symmetry and Binding of Bicyclomycin
Biochemistry, 2000The antibiotic bicyclomycin inhibits rho-dependent termination processes by interfering with RNA translocation by preventing RNA binding at the translocation site or by uncoupling the translocation process from ATP hydrolysis. Previous studies have shown that bicyclomycin binds near the ATP hydrolysis pocket on rho.
F, Vincent +5 more
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Metal Dependency for Transcription Factor Rho Activation
Biochemistry, 2003The Escherichia coli rho transcription termination factor terminates select transcripts and rho activity requires Mg(2+). We investigated whether divalent metal ions other than Mg(2+) catalyze rho-dependent ATP hydrolysis to ADP and P(i) in vitro. The effects of 11 divalent metal ions (Be(2+), Ca(2+), Cd(2+), Co(2+), Cu(2+), Hg(2+), Mn(2+), Ni(2+), Sr ...
Thomas P, Weber +2 more
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Parallelization of Pollard's Rho Integer factorization algorithm
Proceedings of the Second International Conference on Computational Science, Engineering and Information Technology, 2012In the new era of computing technology, demands legacy algorithms to be adaptable to everchanging hardware architecture. With advent of higher processing capablities, the legacy algorithms needs to be re-designed to suit the state-of-art computing methods to yield maximum and effective utilization of resources.
G. Harish +8 more
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Mastering the control of the Rho transcription factor for biotechnological applications
Applied Microbiology and Biotechnology, 2021The present review represents an update on the fundamental role played by the Rho factor, which facilitates the process of Rho-dependent transcription termination in the prokaryotic world; it also provides a summary of relevant mutations in the Rho factor and the insights they provide into the functions carried out by this protein.
Tomás G. Villa +2 more
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Journal of Molecular Biology, 1996
Escherichia coli nusD strains are bacteria that carry mutations in rho, the gene for transcription termination factor Rho, that block the growth of phages T4 and lambdar32. We have identified the rho mutation in six independent nusD strains, and although five of the strains have different mutations, with one exception the mutations are in the proposed ...
R S, Washburn, B L, Stitt
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Escherichia coli nusD strains are bacteria that carry mutations in rho, the gene for transcription termination factor Rho, that block the growth of phages T4 and lambdar32. We have identified the rho mutation in six independent nusD strains, and although five of the strains have different mutations, with one exception the mutations are in the proposed ...
R S, Washburn, B L, Stitt
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rho factor-dependent transcription termination. Interference by a mutant rho.
Journal of molecular biology, 1987The rho protein isolated from a strain of Escherichia coli with the rho1 (suA1) mutant allele is defective in interactions with RNA that are coupled to ATP hydrolysis. Here we show that the rho1 allele is partially dominant over wild-type and demonstrate that the mechanism of that dominance is due to an interference of wild-type rho factor function by ...
J P, Richardson, E C, Ruteshouser
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Transcription termination factor rho is an RNA-DNA helicase
Cell, 1987E. coli rho factor can unwind a short RNA-DNA duplex in vitro. The duplex is formed between a polylinker sequence at the 3' end of RNA derived from the rho-dependent terminator trp t' and the complementary sequence in a single-strand DNA molecule. Release of trp t' RNA from the duplex requires nucleoside triphosphate hydrolysis by rho's NTPase activity
C A, Brennan, A J, Dombroski, T, Platt
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Preventing the synthesis of unused transcripts by rho factor
Cell, 1991John P. Richardson Department of Chemistry Programs in Biochemistry and Molecular, Cellular and Developmental Biology Indiana University Bloomington, Indiana 47405 Transcriptional terminators have three important functions in gene expression. One is as asignal that defines the end of transcription unit for a gene or a group of genes.
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Transcription termination factor Rho and microbial phenotypic heterogeneity
Current Genetics, 2017Populations of genetically identical microorganisms exhibit high degree of cell-to-cell phenotypic diversity even when grown in uniform environmental conditions. Heterogeneity is a genetically determined trait, which ensures bacterial adaptation and survival in the ever changing environmental conditions.
Elena Bidnenko, Vladimir Bidnenko
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Overproduction of transcription termination factor Rho in Escherichia coli
Gene, 1984A plasmid system has been constructed which allows high-level expression of the rho gene of Escherichia coli under the control of the pL promoter and the N-antitermination regulatory system of bacteriophage lambda. The pL-directed synthesis of Rho crucially depends on the lambda N gene product and is promoted most effectively when this product is ...
K, Shigesada +3 more
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