Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li +14 more
wiley +1 more source
Cinnamaldehyde Inhibits Leptin-Induced MMP-1 by Modulating Leptin Receptor/STAT3 and Blocking RhoA/NF-κB Pathways in Human Intervertebral Disc Stem Cells. [PDF]
Hua KF, Yu HC, Hsu HT.
europepmc +1 more source
Endothelial Nucleoporin93 (Nup93) Maintains Vascular Function via Sun1-Dependent Regulation of RhoA-eNOS Signaling [PDF]
Tung Nguyen +10 more
openalex +1 more source
Primary Cutaneous Peripheral T‐Cell Lymphoma With Follicular Helper T‐Cell Phenotype
ABSTRACT An otherwise healthy 82‐year‐old woman presented with recurrent, asymptomatic erythematous papulo‐nodular lesions on the face and extremities. A skin biopsy revealed a dense, non‐epidermotropic lymphohistiocytic infiltrate with granulomatous features and a mixed population of medium‐sized atypical lymphoid cells and plasma cells ...
Nidia Planella‐Fontanillas +9 more
wiley +1 more source
Kinesin-1 coordinates cross-talk between microtubule and actin cytoskeletons during dendritic cell migration. [PDF]
Duquesne P +19 more
europepmc +1 more source
EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation [PDF]
Seth S. Margolis +12 more
openalex +1 more source
Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty +2 more
wiley +1 more source
Cilostazol-inhibited RhoA/NF-κB signaling mitigates hippocampal inflammation and post-stroke depression. [PDF]
Zhang Y +5 more
europepmc +1 more source

