PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Facile Fabrication of Carbon Paper-Supported Fe Catalyst Under Pulse Laser Irradiation for Degradation of Rhodamine B. [PDF]
Bai W, Chang F, Fan X, Tian W.
europepmc +1 more source
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul +12 more
wiley +1 more source
Synthesis and characterization of trimetallic (CuNiZn-PDC) MOF for the effective remediation of Rhodamine B dye. [PDF]
Alam S +6 more
europepmc +1 more source
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Carbon-Modified Attapulgite Composite for Rapid Rhodamine B Degradation: High Adsorption Capacity and Photo-Fenton Efficiency. [PDF]
Karim N +5 more
europepmc +1 more source
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
Cu(ii)-modified Mg-Al hydrotalcite/bentonite composites for adsorption and visible-light-driven photocatalytic degradation of Rhodamine B in textile wastewater. [PDF]
Vu VN +4 more
europepmc +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Nonlinear Kinetics and Isotherm Modeling of Rhodamine B Adsorption onto Al<sub>2</sub>O<sub>3</sub> Decorated Laponite. [PDF]
Erden L, Deveci İ, Erden H.
europepmc +1 more source

