Results 1 to 10 of about 69,355 (271)
Unexpected microbial rhodopsin dynamics in sync with phytoplankton blooms [PDF]
Nature CommunicationsThe surface ocean is the largest sunlit environment on Earth where marine microalgae are known as the main drivers of global productivity. However, rhodopsin phototrophs are actually the most abundant metabolic group, suggesting a major role in the ...
Laura Gómez-Consarnau +9 more
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A key amino acid site associated with rhodopsin mammal evolution to diurnal vision [PDF]
Scientific ReportsRhodopsin is a photoreceptor protein found in the vertebrate retina used as a landmark for vision evolution studies at the molecular level. Here, we examined the biochemical and functional performance of modern rhodopsin from three different mammal ...
Miguel A. Fernández-Sampedro +4 more
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Scientific Reports, 2022 Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a misfolded rhodopsin protein that photoreceptors quickly target for degradation by mechanisms that are
Kyle Kim +5 more
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PLoS ONE, 2023 We aimed to verify whether the intravitreal injection of small molecule compounds alone can create photoreceptor cells in mouse models of retinal degeneration.
Yuya Fujii +3 more
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Discovery of a microbial rhodopsin that is the most stable in extreme environments
iScience, 2021 Summary: Microbial rhodopsin is a retinal protein that functions as an ion pump, channel, and sensory transducer, as well as a light sensor, as in biosensors and biochips.
Jin-gon Shim +9 more
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Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant. [PDF]
PLoS ONE, 2012 Two outstanding unknowns in the biology of photoreceptors are the molecular determinants of cell size, which is remarkably uniform among mammalian species, and the mechanisms of rod cell death associated with inherited neurodegenerative blinding diseases
Brandee A Price +6 more
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Scientific Reports, 2021 Retinitis Pigmentosa (RP) is a blinding disease that arises from loss of rods and subsequently cones. The P23H rhodopsin knock-in (P23H-KI) mouse develops retinal degeneration that mirrors RP phenotype in patients carrying the orthologous variant ...
Eun-Jin Lee +5 more
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STAR Protocols, 2022 Summary: Microbial rhodopsins are photoreceptive membrane proteins showing various light-dependent biological activities. Styrene-maleic acid (SMA) copolymers spontaneously form nanoscale lipid particles containing membrane proteins and associated lipids
Keiichi Kojima, Yuki Sudo
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Ion-pumping microbial rhodopsin protein classification by machine learning approach
BMC Bioinformatics, 2023 Background Rhodopsin is a seven-transmembrane protein covalently linked with retinal chromophore that absorbs photons for energy conversion and intracellular signaling in eukaryotes, bacteria, and archaea.
Muthu Krishnan Selvaraj +6 more
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Violet light down-regulates the expression of specific differentiation markers through Rhodopsin in normal human epidermal keratinocytes. [PDF]
PLoS ONE, 2013 Several recent reports have demonstrated that photoreceptors are expressed in human skin. The rod and cone photoreceptor-like proteins are expressed in human skin and rhodopsin, long wavelength-opsin, and short wavelength-opsin are also present in ...
Hyoung-June Kim +5 more
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