Results 31 to 40 of about 38,017 (242)
Rhodopsin phylogenetics with Comchoano
, 2022 #rhodopsin alignment, fasta file untrimmedrhodopsin_alignment_mafft.w.gtdb.0.99.ordered.best.hits.and.ubas.and.changjae.fa.list.fa#rhodopsin alignment, fasta file trimmedrhodopsin_trimmed_alignment_trimal.mafft.w.gtdb.0.99.ordered.best.hits.and.ubas.and ...
David Needham (757445)
core +1 more source
Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics. [PDF]
PLoS ONE, 2012 The retinal rod outer segment is a sensory cilium that is specialized for the conversion of light into an electrical signal. Within the cilium, up to several thousand membranous disks contain as many as a billion copies of rhodopsin for efficient photon ...
Clint L Makino +7 more
doaj +1 more source
iScience, 2023 Summary: Photoreception requires amplification by mammalian rhodopsin through G protein activation, which requires a visual cycle. To achieve this in retinal gene therapy, we incorporated human rhodopsin cytoplasmic loops into Gloeobacter rhodopsin ...
Yusaku Katada +9 more
doaj +1 more source
Isoelectric Focusing to Quantify Rhodopsin Phosphorylation in Mouse Retina
Bio-Protocol, 2019 Rhodopsin is a G-protein coupled receptor (GPCR) that mediates vision under dim light. Upon light exposure, rhodopsin is phosphorylated at multiple serine and threonine sites at its carboxyl-terminus by rhodopsin kinase (GRK1). This, in turn, reduces its
Sowmya Bekshe Lokappa +2 more
doaj +1 more source
PLoS Genetics, 2021 Color vision in Drosophila melanogaster is based on the expression of five different color-sensing Rhodopsin proteins in distinct subtypes of photoreceptor neurons.
Clara Poupault +8 more
doaj +1 more source
Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice. [PDF]
PLoS ONE, 2014 For sensitive detection of rare gene repair events in terminally differentiated photoreceptors, we generated a knockin mouse model by replacing one mouse rhodopsin allele with a form of the human rhodopsin gene that causes a severe, early-onset form of ...
Ivette M Sandoval +6 more
doaj +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi +7 more
core +1 more source
Negative regulation of the novel norpA(P24) suppressor, diehard4, in the endo-lysosomal trafficking underlies photoreceptor cell degeneration. [PDF]
PLoS Genetics, 2013 Rhodopsin has been used as a prototype system to investigate G protein-coupled receptor (GPCR) internalization and endocytic sorting mechanisms. Failure of rhodopsin recycling upon light activation results in various degenerative retinal diseases ...
Jongwoo Lee +2 more
doaj +1 more source
Binding of rhodopsin and rhodopsin analogues to transducin, rhodopsin kinase and arrestin-1
World Journal of Biological Chemistry, 2014 Laparoscopic surgery is the main treatment method for patients with gastrointestinal malignant tumors. Although laparoscopic surgery is minimally invasive, its tool stimulation and pneumoperitoneum pressure often cause strong stress reactions in patients. On the other hand, gastrointestinal surgery can cause stronger pain in patients, compared to other
Nelson A, Araujo +2 more
openaire +2 more sources
Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation.
PLoS ONE, 2011 The P23H mutation in the rhodopsin gene causes rhodopsin misfolding, altered trafficking and formation of insoluble aggregates leading to photoreceptor degeneration and autosomal dominant retinitis pigmentosa (RP).
Vidyullatha Vasireddy +8 more
doaj +1 more source