Neuromorphic Devices and Computing for Sensing, Memory, and Control
Advanced Science, EarlyView.This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Innovative Approach Reveals How Receptors Control G Protein State Equilibria
Advanced Science, EarlyView.Using conformational specific trFRET biosensors of the Gi protein (depicted at the bottom), the authors show that receptor activation can not only release GDP from the inactive G protein, but can also release GTP from the activated G protein, leading to the reformation of the RG ternary complex.
Alexandre Bouyssou +12 more
wiley +1 more source
The Evolutionary Relationship between Microbial Rhodopsins and Metazoan Rhodopsins [PDF]
The Scientific World Journal, 2013 Rhodopsins are photoreceptive proteins with seven‐transmembrane alpha‐helices and a covalently bound retinal. Based on their protein sequences, rhodopsins can be classified into microbial rhodopsins and metazoan rhodopsins. Because there is no clearly detectable sequence identity between these two groups, their evolutionary relationship was difficult ...
Libing Shen +3 more
openaire +3 more sources
A Y178C rhodopsin mutation causes aggregation and comparatively severe retinal degeneration
Cell Death DiscoveryRhodopsin is the light-activated G protein-coupled receptor that initiates vision in photoreceptor cells of the retina. Numerous mutations in rhodopsin promote receptor misfolding and aggregation, causing autosomal dominant retinitis pigmentosa, a ...
Sreelakshmi Vasudevan, Paul S.–H. Park
doaj +1 more source
eLife, 2023 Even though microbial photosensitive proteins have been used for optogenetics, their use should be optimized to precisely control cell and tissue functions in vivo.
Hanako Hagio +10 more
doaj +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Major Reference Works., 2011 Wiley is pleased to announce the recent acquisition of the prestigious Encyclopedia of Life Sciences (ELS) from the Nature Publishing Group.
"The most ambitious single source reference source ever produced in the biological sciences"
—American Reference Books Annual
Spanning the entire spectrum of life science ...
Peter Hegemann, Carol Dieckmann
wiley +1 more source
Capturing a rhodopsin receptor signalling cascade across a native membrane [PDF]
, 2022 G protein-coupled receptors (GPCRs) are cell-surface receptors that respond to various stimuli to induce signalling pathways across cell membranes. Recent progress has yielded atomic structures of key intermediates1,2 and roles for lipids in signalling3 ...
Robinson, Carol V +15 more
core +1 more source
Functional Expression of Gloeobacter Rhodopsin in PSI-Less Synechocystis sp. PCC6803
Frontiers in Bioengineering and Biotechnology, 2019 The approach of providing an oxygenic photosynthetic organism with a cyclic electron transfer system, i.e., a far-red light-driven proton pump, is widely proposed to maximize photosynthetic efficiency via expanding the absorption spectrum of ...
Que Chen +9 more
doaj +1 more source
mSystems, 2023 Microbial rhodopsins are found more than once in a single genome (paralogs) often have different functions. We screened a large dataset of open ocean single-amplified genomes (SAGs) for co-occurrences of multiple rhodopsin genes.
Jose M. Haro-Moreno +7 more
doaj +1 more source