Results 91 to 100 of about 61,046 (231)
Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice [PDF]
Journal of Biological Chemistry, 2004 Rhodopsin (Rho) resides within internal membrane structures called disc membranes that are found in the rod outer segments (ROS) of photoreceptors in the retina. Rho expression is essential for formation of ROS, which are absent in knockout Rho-/- mice.
Liang, Y. +8 more
openaire +2 more sources
Disc antenna enhanced infrared spectroscopy: From felf-assembled monolayers to membrane proteins [PDF]
, 2018 Plasmonic surfaces have emerged as a powerful platform for biomolecular sensing applications and can be designed to optimize the plasmonic resonance for probing molecular vibrations at utmost sensitivity.
Ataka, Kenichi +4 more
core +1 more source
The oscillatory response of the electroretinogram and neuronal adaptation
Acta Ophthalmologica, EarlyView.Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Persistent activation of transducin by bleached rhodopsin in salamander rods. [PDF]
, 1996 The hydrolysis-resistant GTP analogue GTP-gamma-S was introduced into rods isolated from the retina of the salamander Ambystoma tigrinum to study the origin of the persistent excitation induced by intense bleaching illumination.
Cornwall, MC, Fain, GL, Matthews, HR
core
Cell Proliferation, EarlyView.The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
Binding of rhodopsin and rhodopsin analogues to transducin, rhodopsin kinase and arrestin-1
World Journal of Biological Chemistry, 2014 Laparoscopic surgery is the main treatment method for patients with gastrointestinal malignant tumors. Although laparoscopic surgery is minimally invasive, its tool stimulation and pneumoperitoneum pressure often cause strong stress reactions in patients. On the other hand, gastrointestinal surgery can cause stronger pain in patients, compared to other
Nelson A, Araujo +2 more
openaire +2 more sources
Direct stimulation of the retina by the method of virtual-quanta for heavy cosmic-ray nuclei [PDF]
, 1972 The contribution to the frequency of visual sensations induced in the dark-adapted eye by the virtual photon field was calculated, this field is associated with the heavy nuclei that exist in space beyond the geomagnetic field.
Madey, R., Mcnulty, P. J.
core +1 more source
Cell Proliferation, EarlyView.Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
A Multi-Scale–Multi-Stable Model for the Rhodopsin Photocycle
Molecules, 2014 We report a multi-scale simulation study of the photocycle of the rhodopsins. The quasi-atomistic representation (“united atoms” UA) of retinal is combined with a minimalist coarse grained (CG, one-bead-per amino acid) representation of the protein, in a
Francesco Tavanti, Valentina Tozzini
doaj +1 more source