Results 111 to 120 of about 38,017 (242)

Circadian rhythms in the Drosophila eye may regulate adaptation of vision to light intensity

Frontiers in Neuroscience
The sensitivity of the eye at night would lead to complete saturation of the eye during the day. Therefore, the sensitivity of the eye must be down-regulated during the day to maintain visual acuity.
Richard Brent Nolan, Jin-Yuan Fan, Jeffrey L. Price   +2 more
doaj   +1 more source

Retention of the Full Visual Opsin Repertoire in Some Australian Cryptozoic Lizards

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study investigates the link between visual evolution and fossorial habits in the endemic Australian skink genus Lerista. We provide evidence for positive site‐specific selection in all 4 cone opsins, as well as relaxed selection specific to LWS. We also provide evidence of selection linked to limb reduction, an indicator of fossorial adaptation ...
Matthew J. R. Ford, Alastair J. Ludington, Tessa Bradford, Kate L. Sanders, Mark N. Hutchinson, Bruno F. Simões   +5 more
wiley   +1 more source

Calcium-bound recoverin targets rhodopsin kinase to membranes to inhibit rhodopsin phosphorylation

, 1996
In rod photoreceptor cells, Ca2+-bound recoverin associates with disk membranes and inhibits light-dependent phosphorylation of rhodopsin. However, the functional significance of Ca2+-induced membrane association of recoverin has not been fully evaluated.
Kamon Sanada, Yoshitaka Fukada, Haga, Kazuko, Kameyama, Kimihiko, Kimihiko Kameyama, Sanada, Kamon, Fumiko Shimizu, Shimizu, Fumiko, Kazuko Haga, Fukada, Yoshitaka, Haga, Tatsuya, Tatsuya Haga   +11 more
core   +1 more source

Mutant dominant-negative rhodopsin∆I256 causes protein aggregates degraded via ERAD and prevents normal rhodopsin from proper membrane trafficking

Frontiers in Molecular Biosciences
Dominant mutations in the rhodopsin gene (Rho) contribute to 25% of autosomal dominant retinitis pigmentosa (adRP), characterized by photoreceptor loss and progressive blindness. One such mutation, Rho∆I256, carries a 3-bp deletion, resulting in the loss
Bowen Cao, Bowen Cao, Johanna Valentina Dahlen, Merve Sen, Merve Sen, Tina Beyer, Tobias Leonhard, Ellen Kilger, Blanca Arango-Gonzalez, Marius Ueffing   +9 more
doaj   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Adeno-associated virus mediated rhodopsin delivery in preventing secondary cone degeneration in rhodopsin knockout mice

, 2016
Rhodopsin-linked retinitis pigmentosa (RP) is the most common form of autosomal dominant RP, an inherited retinal degeneration, in which rod degeneration is followed by secondary cone loss leading to loss of vision and blindness. The overall objective of
Daniyar Dauletbekov, Dauletbekov, Daniyar   +1 more
core   +1 more source

Shine Amidst Darkness—A Case of Oguchi Disease

TNOA Journal of Ophthalmic Science and Research
An 11-year-old boy presented with complaints of defective night vision. Visual acuity was 6/6 in both eyes. The fundus showed a golden-to-grey discoloration in light and on dark adaptation, the fundus reverted to its normal appearance demonstrating the ...
R Padmapriya, Fathima Fahima Akbar
doaj   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt

, 1995
The cytoplasmic loops of rhodopsin, the rod cell photoreceptor, play important regulatory roles in the activation of both rhodopsin kinase and the rod cell G protein, Gt. A number of studies have identified domains in rhodopsin that are important for the
Dickerson, Charlene D., Weiss, Ellen R., Shi, Wen, Osawa, Shoji   +3 more
core   +1 more source

Localization and dimer stability of a newly identified microbial rhodopsin from a polar, non-motile green algae

BMC Research Notes, 2018
Objective The eukaryotic plasma membrane localized light-gated proton-pumping rhodopsins possesses great optogenetic applications for repolarization (silencing) of the neuronal activity simply by light illumination.
Peeyush Ranjan, Suneel Kateriya
doaj   +1 more source