Results 81 to 90 of about 41,721 (227)
Frontiers in Molecular Neuroscience, 2018 We determined the effects of different expression levels of arrestin-1-3A mutant with enhanced binding to light-activated rhodopsin that is independent of phosphorylation.
Srimal Samaranayake +5 more
doaj +1 more source
The FEBS Journal, EarlyView.Distinct GPCR phosphorylation barcodes and arrestin conformational states direct arrestin‐mediated signaling and trafficking. The graphical abstract depicts the structural diversity of GPCR–arrestin complexes by overlaying representative core‐engaged and tail‐engaged conformations.
Varsha Gupta +1 more
wiley +1 more source
Relevance of rhodopsin studies for GPCR activation
, 2014 Rhodopsin, the dim-light photoreceptor present in the rod cells of the retina, is both a retinal-binding protein and a G protein-coupled receptor (GPCR). Due to this conjunction, it benefits from an arsenal of spectroscopy techniques that can be used for
Xavier Deupi +2 more
core +1 more source
Adeno-associated virus mediated rhodopsin delivery in preventing secondary cone degeneration in rhodopsin knockout mice [PDF]
, 2017 Rhodopsin-linked retinitis pigmentosa (RP) is the most common form of autosomal dominant RP, an inherited retinal degeneration, in which rod degeneration is followed by secondary cone loss leading to loss of vision and blindness. The overall objective of
core +1 more source
Adaptation to extreme environments: A review of Antarctic fish physiology
Journal of Fish Biology, EarlyView.Abstract Having evolved in the chronically cold and thermally stable waters of the Southern Ocean (SO) for millions of years, Antarctic fish possess a suite of physiological specializations that enable them to survive at temperatures near the freezing point of seawater. Adaptations include the evolution of antifreeze proteins, modifications of membrane
Seungyeon Lee +8 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena +4 more
wiley +1 more source
, 1992 With the aim of preparing a light-stable rhodopsin-like pigment, an analog, II, of 11-cis retinal was synthesized in which isomerization of the C11-C12 cis-double bond is blocked by a cyclohexene ring built around the C10 to C13-methyl.
Khorana, H. G. +3 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Analyses from mutant mouse retinal explants gives invaluable insights of the photosignaling process in rod and cone photoreceptor cells. A, Illustration of retinal photovoltage recordings. A retinal explant (pink) is placed in a transparent device which has electrodes to monitor transretinal voltage (red and blue circles).
Shinya Sato +3 more
wiley +1 more source
Rhodopsin 7-The unusual Rhodopsin in Drosophila
, 2020 Rhodopsins are the major photopigments in the fruit fly Drosophila melanogaster. Drosophila express six well-characterized Rhodopsins (Rh1-Rh6) with distinct absorption maxima and expression pattern.
Pingkalai R Senthilan +1 more
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Characterization of rhodopsin kinase purified from bovine rod outer segments [PDF]
, 2008 Rhodopsin kinase was purified by sequential chromatography on DEAE-cellulose and blue-Sepharose. Kinase activity co-purified with a 62-kDa polypeptide, which bound light-dependently in the absence of ATP to purified vesicle-reconstituted rhodopsin ...
Johnson, Gary L., Kelleher, Daniel J.
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