Results 11 to 20 of about 69,829 (275)

Ribavirin for treating Lassa fever: A systematic review of pre-clinical studies and implications for human dosing.

open access: yesPLoS Neglected Tropical Diseases, 2022
Ribavirin is currently the standard of care for treating Lassa fever. However, the human clinical trial data supporting its use suffer from several serious flaws that render the results and conclusions unreliable.
Alex P Salam   +7 more
doaj   +2 more sources

Enzymatic Production of Ribavirin [PDF]

open access: bronzeAgricultural and Biological Chemistry, 1988
Criblage de 400 souches bacteriennes afin de selectionner des bacteries capables de produire du ribose (phosphate-1) a partir de l'inosine ou de la ribavirine (antiviral) a partir du ribose (phosphate-1), grâce a leur activite purine-nucleoside phosphorylase.
Hideyuki Shirae   +2 more
openalex   +4 more sources

Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID‐19

open access: yesJournal of Medical Virology, 2021
This trial compared the rate and time of viral clearance in subjects receiving a combination of nitazoxanide, ribavirin, and ivermectin plus Zinc versus those receiving supportive treatment.
H. Elalfy   +14 more
semanticscholar   +1 more source

Ribavirin

open access: yesThe Saudi Journal of Gastroenterology, 2001
Al Knawy Bandar
doaj   +2 more sources

The impact of sofosbuvir/daclatasvir or ribavirin in patients with severe COVID-19

open access: yesJournal of Antimicrobial Chemotherapy, 2020
Objectives Sofosbuvir and daclatasvir are direct-acting antivirals highly effective against hepatitis C virus. There is some in silico and in vitro evidence that suggests these agents may also be effective against SARS-CoV-2.
G. Eslami   +21 more
semanticscholar   +1 more source

Psychomotor activity and body weight gain after exposure to low ribavirin doses in rats: role of treatment duration [PDF]

open access: yesArchives of Biological Sciences, 2019
Clinically-related basic studies on the behavioral effects of ribavirin treatment are still lacking despite its wide use as an antiviral medication. This paper considers the effects of low ribavirin doses (10, 20 and 30 mg/kg/day) on psychomotor activity
Petković Branka   +6 more
doaj   +1 more source

Combined therapy with danazol, pegilated interferon, and ribavirin improves thrombocytopenia and liver injury in rats with fibrosis

open access: yesAnnals of Hepatology, 2007
The aim of this study was to investigate the effects of combinations of pegilated–interferon (PEG–IFN), ribavirin, and danazol on thrombocytopenia and liver injury in rats with fibrosis.
Guillermo Cabrera Álvarez   +7 more
doaj   +1 more source

Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV. [PDF]

open access: yesPLoS ONE, 2011
The nucleoside analogue Ribavirin significantly increases patient response to IFN-α treatment of HCV, by directly inhibiting viral replication. Recent studies indicate that Ribavirin also regulates immunity and we propose that Ribavirin enhances specific
Nigel J Stevenson   +5 more
doaj   +1 more source

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis. [PDF]

open access: yesPLoS ONE, 2013
Lethal mutagenesis, or virus extinction produced by enhanced mutation rates, is under investigation as an antiviral strategy that aims at counteracting the adaptive capacity of viral quasispecies, and avoiding selection of antiviral-escape mutants.
Ana M Ortega-Prieto   +8 more
doaj   +1 more source

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