Results 21 to 30 of about 47,954 (202)
Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]
, 2003 Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.Konig, A., Folwaczny, Christian, Schmidt, F., Simperl, C., Schaefer, M., Torok, P., Glas, J., Schiemann, Uwe, Martin, K. +8 morecore +1 more sourceAdding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]
, 2000 Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.Amann, B., Schmidt, F., Schlösser, S., Loeschke, K., Grunze, Heinz, Schäfer, Martin +5 morecore +1 more sourceLack of Evidence for Ribavirin Treatment of Lassa Fever in Systematic Review of Published and Unpublished Studies
Emerging Infectious Diseases, 2022
Ribavirin has been used widely to treat Lassa fever in West Africa since the 1980s. However, few studies have systematically appraised the evidence for its use.Hung-Yuan Cheng, Clare E. French, Alex P. Salam, Sarah Dawson, Alexandra McAleenan, Luke A. McGuinness, Jelena Savović, Peter W. Horby, Jonathan A.C. Sterne +8 moredoaj +1 more sourceResponse prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms [PDF]
, 2011 Background: High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C.Askarieh Galia, Neumann, A.U. (Avidan), Söderholm, Jonas,, Magnus Lindh, Avidan U Neumann, Stephanie Bibert, Soderholm, J, Askarieh, Galia,, Romero, A. (Ana), Group, DITTO-HCV Study, Jean-Michel Pawlotsky, Lindh, M., Negro, F, Söderholm, J., Lindh, M, Missale, Gabriele, Lagging, Martin,, Askarieh, G., Haagmans, Bart L, Romero, Ana, Hellstrand, K. (Kristoffer), Bochud Pierre-Yves, Lagging, Martin, Romero, A, null null, Söderholm Jonas, Haagmans, Bart L., Neumann, AU (Avidan), Gabriele Missale, Ferrari, C., Negro, F., Pawlotsky, J.M., Lindh Magnus, Negro Francesco, Avidan U. Neumann, Pierre-Yves Bochud, Lindh, Magnus, Johan Westin, Zeuzem Stefan, Lindh, M. (Magnus), Missale Gabriele, Bochud, Pierre Yves, Bibert, S., Bochud, P.Y., Galia Askarieh, Lagging Martin, Ferrari Carlo, Bibert, Stephanie, Hellstrand, Kristoffer, Zeuzem, S., Neumann, Avidan U., Haagmans, B.L., DITTO-HCV Study Group, Neumann, A.U., Lindh, Magnus,, Francesco Negro, Westin, J., Söderholm, J. (Jonas), Zeuzem, S. (Stefan), Söderholm, Jonas, Ferrari, Carlo, Martin Lagging, Neumann Avidan U., Zeuzem, Stefan, Neumann, Avidan U, Zeuzem, S, Hellstrand Kristoffer, Westin, Johan, Bart L Haagmans, Romero, A., Lagging, M. (Martin), Hellstrand, K., Haagmans, Bart, Bibert Stephanie, Hellstrand, K, Bart L. Haagmans, Missale, G. (Gabriele), Pawlotsky, Jean Michel, Pawlotsky, Jean-Michel, Ferrari, C. (Carlo), Carlo Ferrari, Bochud, P-Y. (Pierre-Yves), Haagmans Bart L., Askarieh, G, Lagging, M., Missale, G., Stefan Zeuzem, Kristoffer Hellstrand, Ferrari, C, Westin, J. (Johan), Askarieh, Galia, Bibert, S, Lagging, M, Westin, Johan,, Hellstrand, Kristoffer,, Westin, J, Haagmans, B.L. (Bart), Romero Ana, Jonas Söderholm, Pawlotsky Jean-Michel, Westin Johan, Askarieh, G. (Galia), Negro, Francesco, Bochud, PY, Bochud, Pierre-Yves, Pawlotsky, JM, Pawlotsky, J-M. (Jean-Michel), Missale, G, Romero, Ana,, Ana Romero +109 morecore +1 more sourceIL28B, HLA-C, and KIR variants additively predict response to therapy in chronic Hepatitis C virus infection in a European cohort: A cross-sectional study [PDF]
, 2011 Background
To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-Hellard, M, Powell, Elizabeth, Ahlenstiel, G., Smedile, Antonina, Bassendine, Margaret, Hammond, E., O'Connor, Kate S, Armstrong, Nicola J, Stewart, Graeme J, Müller Tobias, Silvana Gaudieri, Mallal Simon, Armstrong Nicola J., Powell Elizabeth, Graeme J Stewart, Bassendine, M, Abate, ML, Jacob Nattermann, Irving, WL, Ahlenstiel, G, Simon Mallal, Negro, F, Stewart, Graeme J., Suppiah, Vijayaprakash, Matthews, G, Suppiah Vijayaprakash, Gaudieri Silvana, Bochud Pierre-Yves, null null, Nattermann, J, Vijayaprakash Suppiah, Hammond, Emma, Graeme J. Stewart, Hellard Margaret, Bochud, P-Y, Mallal, S., Negro, F., Ahlenstiel, Golo (R18999), O'Connor, KS, Smedile, A, Booth, DR, Powell, E, George Jacob, Gaudieri, S., Negro Francesco, Pierre-Yves Bochud, Irving, W.L., David Dunn, Abate, Maria L., Dore Gregory J., Hellard, M., International Hepatitis C Genetics Consortium (IHCGC), Spengler, U., William L Irving, Dunn David, David Sheridan, Riordan Stephen, Berg Thomas, Dunn, D.S., Stewart Graeme J., Mathews, Gail, Weltman, Martin, Ulrich Spengler, Nattermann Jacob, Mallai, Simon, Dunn, D, Francesco Negro, Berg, Thomas, for the International Hepatitis C Genetics Consortium (IHCGC), Gregory J. Dore, Sheridan, D, Abate Maria Lorena, Jacob George, Nicola J Armstrong, Matthews Gail, Mallal, S, Matthews, Gail, Booth, David R, Dore, G.J., Müller, T., Kate S O'Connor, Armstrong, Nicola J., Dore, Gregory J, Gail Matthews, Spengler Ulrich, Müller, T, Booth, David R., Berg, T., Irving, William L., Spengler, U, Booth, D.R., Spengler, Ulrich, Suppiah, V, Powell, E., Martin Weltman, Emma Hammond, Dunn, David, Thomas Berg, Suppiah, Vijay, Matthews, G., Abate, Maria Lorena, Bassendine, M., Berg, T, Riordan, Stephen, Hammond, E, Muller, Tobias, Ahlenstiel, Golo, Nattermann, J., Sheridan David, Smedile Antonina, Kate S. O'Connor, Mallal, Simon, Sheridan, D., Hammond Emma, David R. Booth, Irving William L., Stewart, GJ, Maria Lorena Abate, O'Connor, Kate S., Antonina Smedile, Golo Ahlenstiel, Armstrong, N.J., Margaret Hellard, Dore, GJ, O'Connor Kate S., Gaudieri, S, Hellard, Margaret, David R Booth, Weltman Martin, Riordan, S, Irving, William L, Margaret Bassendine, Tobias Müller, Armstrong, NJ, Weltman, M., Bassendine Margaret, Booth David R., Elizabeth Powell, Smedile, A., William L. Irving, Dore, Gregory J., Stephen Riordan, Weltman, M, Sheridan, David, Negro, Francesco, Bochud, PY, Riordan, S., Bochud, Pierre-Yves, Gregory J Dore, O'Connor, K.S., George, J, Nicola J. Armstrong, Suppiah, V., Stewart, G.J., Ahlenstiel Golo, George, J., George, Jacob, Nattermann, Jacob, Abate, M.L., Gaudieri, Silvana +159 morecore +1 more sourceHepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials [PDF]
, 2012 Background: In patients with genotype 1 chronic hepatitis C infection, telaprevir (TVR) in combination with peginterferon and ribavirin (PR) significantly increased sustained virologic response (SVR) rates compared with PR alone.Bambang Adiwijaya, Joan Spanks, Ann Tigges (171451), Ann Tigges, Joan Spanks (171460), Zhang Eileen Z., Maria Beumont, Bartels Doug J., De Meyer, Sandra, Jacobson, Ira M., Ira M. Jacobson (171497), Kieffer Tara L., Ghys Anne, Min Jiang, Sullivan James C., James C Sullivan, Doug J Bartels, Beumont, Maria, Dorrian Jennifer, Dierynck, Inge, Nathalie Adda, Adiwijaya, Bambang, Kauffman, Robert S., Kwong, Ann D., Min Jiang (56794), Jennifer Dorrian (171464), James C. Sullivan (13811), Bambang Adiwijaya (171470), Sherman, Kenneth E., Dierynck Inge, Ann D. Kwong (171515), Ghys, Anne, Tara L Kieffer, Gaston Picchio, Maria Beumont (171481), Spanks Joan, Inge Dierynck, Kenneth E Sherman, Robert S Kauffman, Adda Nathalie, Sherman Kenneth E., Stefan Zeuzem (22856), Stefan Zeuzem, Inge Dierynck (171456), Jiang, Min, Robert S. Kauffman (171487), Gaston Picchio (171523), Kwong Ann D., Zhang, Eileen Z., Sandra De Meyer (171427), Tigges, Ann, Zeuzem Stefan, Dorrian, Jennifer, Kenneth E. Sherman (171505), Sandra De Meyer, Nathalie Adda (171493), Jacobson Ira M., Adiwijaya Bambang, Ira M Jacobson, Bartels, Doug J., Doug J. Bartels (171434), Eileen Z Zhang, Jennifer Dorrian, De Meyer Sandra, Tigges Ann, Sullivan, James C., Picchio, Gaston, Ann D Kwong, Anne Ghys (171476), Adda, Nathalie, Eileen Z. Zhang (171445), Kieffer, Tara L., Spanks, Joan, Picchio Gaston, Kauffman Robert S., Anne Ghys, Tara L. Kieffer (171419), Jiang Min, Zeuzem, Stefan, Beumont Maria +79 morecore +1 more sourceIL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population [PDF]
, 2012 <p><b>Background:</b> The interleukin-28B gene (IL28B) locus has been associated with host resistance to hepatitis C virus (HCV) infection and response to PEG-IFN/RBV treatment in western populations. This study was to determine whether Bing Sun, Tao Jiang, Sun Bing, Jiang Jing, Wanyu Li, Moli Wang (162501), Xu Damo, Gao, Y., Damo Xu (162552), Moli Wang, Peng Zhang (2071), Wang Dongsheng, Jiang Yanfang, Wang, M,, Sun, B., Zhong, J., Zhang, P., Shi, X., Tao Jiang (28401), Yanhang Gao, Peng Zhang, Jiang Tao, Junqi Niu (133004), Gao Yanhang, Pan Yu, Jing Jiang (130103), Wang, D., Wang Moli, Jin Zhong, Chi Xiumei, Jiang, T., Damo Xu, Xiumei Chi, Li, W., Yu Pan, Niu Junqi, Dongsheng Wang (162509), Li Wanyu, Niu, J., Xiumei Chi (162522), Yu Pan (162493), Bing Sun (44691), Dongsheng Wang, Wanyu Li (73254), Jiang, Y., Xu, D., Xiaodong Shi (162487), Shi Xiaodong, Chi, X., Jing Jiang, Junqi Niu, Xiaodong Shi, Yanfang Jiang, Zhong Jin, Jiang, J., Zhang Peng, Jin Zhong (9647), Yanfang Jiang (162530), Yanhang Gao (162536), Pan, Y. +59 morecore +1 more source