Inhibition of tick-borne encephalitis virus in cell cultures by ribavirin
Frontiers in Microbiology, 2023 Tick-borne encephalitis virus (TBEV) belonging to arboviruses is a major member of zoonotic pathogens. TBEV infection causes severe human encephalitis without specific antiviral drugs.
Wan-Da Tang +5 more
doaj +1 more source
A randomized, placebo‐controlled study to evaluate safety and pharmacokinetics of inhaled ribavirin
Clinical and Translational Science, 2022 Ribavirin is an inosine monophosphate dehydrogenase inhibitor. Studies suggest ribavirin aerosol could be a safe and efficacious treatment option in the fight against coronaviruses. However, current treatment is long (12–18 h per day, 3–7 days), limiting
Peter Couroux +6 more
doaj +1 more source
Drug Target Insights, 2007 The effect of the antiviral agent ribavirin given alone or in combination with Silymarin on the development of liver injury induced in rats with carbon tetrachloride (CCl 4 ; 2.8 ml/kg followed by 1.4 ml/kg after one week) was studied. Ribavirin at three
Omar M.E. Abdel Salam M.D., Ph.D. +3 more
doaj +2 more sources
Hepatitis A Virus (HAV) Recurrence and De Novo Hepatitis A Acquired at Time of Liver Transplantation: Comparison of Graft HAV Infection and Viral Kinetics [PDF]
J Viral HepatABSTRACT Hepatitis A virus (HAV) infection is an uncommon indication for liver transplantation, and donor‐derived or transfusion‐associated HAV infection is rare. Data describing HAV recurrence or early acquisition following liver transplantation, particularly with longitudinal quantitative viral kinetics, are limited.
Mutimer D, Latham E, Atabani S, Ijaz S.
europepmc +2 more sources
Psychomotor activity and body weight gain after exposure to low ribavirin doses in rats: role of treatment duration [PDF]
Archives of Biological Sciences, 2019 Clinically-related basic studies on the behavioral effects of ribavirin treatment are still lacking despite its wide use as an antiviral medication. This paper considers the effects of low ribavirin doses (10, 20 and 30 mg/kg/day) on psychomotor activity
Petković Branka +6 more
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Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada [PDF]
, 2003 Although information on efficacy and adverse drug reactions is lacking, ribavirin has been used empirically for the treatment of severe acute respiratory syndrome (SARS). We report common adverse events in 110 patients with suspected or probable SARS who
Dresser, L. +7 more
core +1 more source
Annals of Hepatology, 2007 The aim of this study was to investigate the effects of combinations of pegilated–interferon (PEG–IFN), ribavirin, and danazol on thrombocytopenia and liver injury in rats with fibrosis.
Guillermo Cabrera Álvarez +7 more
doaj +1 more source
Cost-effectiveness of pegylated interferon and ribavirin for patients with chronic hepatitis C treated in routine clinical practice. [PDF]
, 2009 OBJECTIVES: This study assesses whether pegylated interferon and ribavirin is cost-effective compared with no antiviral treatment provided in routine clinical practice, for different patient subgroups.
Grishchenko, Marina +7 more
core +1 more source
Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis. [PDF]
PLoS ONE, 2013 Lethal mutagenesis, or virus extinction produced by enhanced mutation rates, is under investigation as an antiviral strategy that aims at counteracting the adaptive capacity of viral quasispecies, and avoiding selection of antiviral-escape mutants.
Ana M Ortega-Prieto +8 more
doaj +1 more source