Results 51 to 60 of about 69,829 (275)

Randomized Trial Evaluating the Impact of Ribavirin Mono-Therapy and Double Dosing on Viral Kinetics, Ribavirin Pharmacokinetics and Anemia in Hepatitis C Virus Genotype 1 Infection. [PDF]

open access: yesPLoS ONE, 2016
In this pilot study (RibaC), 58 hepatitis C virus (HCV) genotype 1 infected treatment-naïve patients were randomized to (i) 2 weeks ribavirin double dosing concomitant with pegylated interferon-α (pegIFN-α), (ii) 4 weeks ribavirin mono-therapy prior to ...
Jesper Waldenström   +13 more
doaj   +1 more source

Influence of Ribavirin on Mumps Virus Population Diversity

open access: yesViruses, 2021
Frequent mumps outbreaks in vaccinated populations and the occurrence of neurological complications (e.g., aseptic meningitis or encephalitis) in patients with mumps indicate the need for the development of more efficient vaccines as well as specific ...
Mirna Jurković   +5 more
doaj   +1 more source

Exploring the impact of a chemical disinfectant and an antiviral drug for RNA virus management in the Mediterranean fruit fly mass‐rearing

open access: yesInsect Science, EarlyView.
Abstract The Mediterranean fruit fly is an agricultural pest of a wide variety of fruit crops. An effective method to counteract them in the field is through the application of the sterile insect technique, which requires the mass‐production of sterile males.
Luis Hernández‐Pelegrín   +5 more
wiley   +1 more source

Effect of Ribavirin on Hepatitis A Virus Replication In Vitro

open access: yesCanadian Journal of Infectious Diseases, 1992
The effect of ribavirin on fetal Rhesus monkey kidney cells (FRhK-4) acutely or chronically infected with hepatitis A virus was studied. The effect of ribavirin on hepatitis A virus yield as detected by radioimmunoassay in acutely infected FRhK-4 cells ...
Rabindra K Chaudhary, Anton P Andonov
doaj   +1 more source

Systematic Review and Meta-analysis of Postexposure Prophylaxis for Crimean-Congo Hemorrhagic Fever Virus among Healthcare Workers

open access: yesEmerging Infectious Diseases, 2018
We performed a systematic review and meta-analysis on the effectiveness of ribavirin use for the prevention of infection and death of healthcare workers exposed to patients with Crimean-Congo hemorrhagic fever virus (CCHFV) infection. Splashes with blood
Önder Ergönül   +7 more
doaj   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study.

open access: yesGastroenterology, 2015
BACKGROUND & AIMS Patients with detectable hepatitis C virus (HCV) RNA at the time of liver transplantation universally experience recurrent HCV infection.
Michael P. Curry   +24 more
semanticscholar   +1 more source

Harnessing Camalexin as a Sustainable and Ecofriendly Strategy to Control Harmful Phytopathogens

open access: yesPlant Pathology, EarlyView.
We review camalexin, a natural antimicrobial from Brassicaceae plants, which shows broad‐spectrum pathogen control and potential as an ecofriendly crop protection agent, with challenges and future directions. ABSTRACT Camalexin is a natural phytoalexin found in the Brassicaceae family, which has shown antimicrobial activity against diverse microbial ...
Farjana Rahman Lopa   +3 more
wiley   +1 more source

Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis

open access: yesBMC Infectious Diseases, 2010
Background Crimean-Congo hemorrhagic fever epidemics often occur in areas where health services are limited, and result in high case fatality rates. Besides intensive care, ribavirin is often recommended.
G Gail   +3 more
doaj   +1 more source

Incidence, risk factors and impact on virological response of anemia in chronic genotype 2 hepatitis C receiving sofosbuvir plus ribavirin

open access: yesJournal of the Formosan Medical Association, 2020
Background/Purpose: The major dose-limiting toxicity of ribavirin is hemolytic anemia. We investigated the incidence, risk factors and impact on virological response of anemia in chronic hepatitis C genotype 2 patients receiving sofosbuvir plus ribavirin
Chi-Ching Chen   +10 more
doaj   +1 more source

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