Results 51 to 60 of about 44,845 (209)

SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS

Сеченовский вестник, 2017
Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya, E. Ilyushenko, I. Belova, M. V. Sardushkin, N. Guznova, V. Piskunova, A. Dremuk, R. Ibragimova, A. V. Kukharenko   +8 more
doaj  

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells.

PLoS ONE, 2019
Epithelial ovarian cancers are insidious pathologies that give a poor prognosis due to their late discovery and the increasing emergence of chemoresistance. Development of small pharmacological anticancer molecules remains a major challenge.
Anaïs Wambecke, Carine Laurent-Issartel, Johanne Leroy-Dudal, Florence Giffard, Fanny Cosson, Nadège Lubin-Germain, Jacques Uziel, Sabrina Kellouche, Franck Carreiras   +8 more
doaj   +1 more source

In Vitro and In Vivo Toxicity and Antiviral Activity of Rhein Derivatives Against Nervous Necrosis Virus

Aquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
ABSTRACT Rhein has been demonstrated to exhibit antiviral activity against nervous necrosis virus (NNV). As rhein coexists in plants with various structurally analogous natural derivatives and may acquire improved biochemical properties through chemical modification, this study investigated the potential of several natural and synthetic derivatives for
Zhiqing Tian, Shuifang Zhu, Jialong Hu, Yaguang Zhu, Fan Jiang, Haolong Cong   +5 more
wiley   +1 more source

Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. [PDF]

PLoS ONE, 2015
Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear.
Yang Wang, David R McGivern, Liang Cheng, Guangming Li, Stanley M Lemon, Junqi Niu, Lishan Su, Natalia J Reszka-Blanco   +7 more
doaj   +1 more source

Implementing a Multidimensional Nursing Protocol in Dabie Bandavirus‐Induced SFTS With Critical Complications

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT This case demonstrates that a comprehensive, multidimensional nursing protocol—encompassing intensive monitoring, complication‐specific management, and rigorous infection control—is associated with favorable outcomes in this critically ill severe fever with thrombocytopenia syndrome (SFTS) patient with complex comorbidities like Parkinson's ...
Yongping Qiu, Minrui Li, Tingting Li, Jing Liu, Xiaodan Zhu, Shaoqin Zheng, Sha Yang   +6 more
wiley   +1 more source

Respiratory Syncytial Virus Epidemiology During and After Covid‐19 Pandemic in Africa: Systematic Review and Meta‐Analysis

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Respiratory syncytial virus (RSV) is a major agent of acute respiratory infections in children and the elderly. RSV epidemiology has been changed by the since Covid‐19 pandemic and this review aimed to assess the extent of this change in Africa.
Moussa Issa, Adamou Lagare, Goni A. M. Bachir, Arnol Bowo ‐Ngandji, Fatimata Hassane, Larwanou Harouna Magagi, Doutchi Mahamadou, Haoua Seini, Eric Adehossi, Alzouma Mayaki Zoubeirou   +9 more
wiley   +1 more source

Fabrication and evaluation of ribavirin-loaded electrospun nanofibers as an antimicrobial wound dressing

Saudi Pharmaceutical Journal
Background: Skin is regarded as an essential first line of defense against harmful pathogens and it hosts an ecosystem of microorganisms that create a widely diverse skin microbiome.
Khulud A. Alsulami, Abrar A. Bakr, Abdullah A. Alshehri, Alhassan H. Aodah, Fahad A. Almughem, Ali A. Alamer, Lujain A. Alharbi, Deema S. Alsuwayeh, Abdulrahman A. Halwani, Abdullah A. Alamoudi, Haya A. Alfassam, Essam A. Tawfik   +11 more
doaj   +1 more source

Beyond the Usual Suspects: RSV Infection in Patients With Hematological Malignancies Compared to Influenza and SARS‐COV‐2—A Report From the EPICOVIDEHA/EPIRESEHA Registry

American Journal of Hematology, Volume 101, Issue 2, Page 365-375, February 2026.
Jon Salmanton‐García, Francesco Marchesi, Milan Navrátil, Iker Falces‐Romero, Maria Ilaria Del Principe, Jorge Labrador, Klára Piukovics, Verena Petzer, Monika M. Biernat, Michail Samarkos, Dario Leotta, Nicola Fracchiolla, Anna Dąbrowska‐Iwanicka, Antonio Vena, Benjamín Víšek, Yavuz M. Bilgin, Jens Van Praet, Mario Virgilio Papa, Inmaculada Heras Fernando, Francesca Farina, Ľuboš Drgoňa, Josip Batinić, Barbora Weinbergerová, Nurettin Erben, Joanna Drozd‐Sokołowska, Patricia García‐Ramírez, Annarosa Cuccaro, Martin Čerňan, Nicola Sgherza, Tobias Lahmer, Donald C. Vinh, Gaëtan Plantefeve, Alberto López‐García, Chiara Cattaneo, Nikola Pantić, Sofya Khostelidi, Julio Dávila‐Valls, Andrés Soto‐Silva, László Imre Pinczés, Ferenc Magyari, Reham Abdelaziz Khedr, Michelina Dargenio, Martijn Bakker, Igor Stoma, Carolina Garcia‐Vidal, Ildefonso Espigado, Claudio Cerchione, Caterina Buquicchio, Zlate Stojanoski, Gabriele Magliano, Stefanie K. Gräfe, Avinash Aujayeb, Lucia Prezioso, Vladimir Otašević, Maria Merelli, Erica Mackenzie, Andreas Glenthøj, Eleni Gavriilaki, Noha Eisa, Mario Delia, Alessandro Busca, Ahlam Almasari, Tatjana Adžić‐Vukičević, Ivana Urošević, Uluhan Sili, Carolina Miranda‐Castillo, Gustavo‐Adolfo Méndez, Stef Meers, Monia Marchetti, Nicola Coppola, Gökçe Melis Çolak, Darko Antić, Ditte Stampe Hersby, Pellegrino Musto, Milche Cvetanoski, Martin Schönlein, Tommaso Francesco Aiello, Elena Arellano, Davide Nappi, Sonia Martín‐Pérez, Mirjana Mitrović, Raul Cordoba, Romane Prin, Marta Callejas‐Charavia, Gina Varricchio, Martina Bavastro, Alessandro Limongelli, Amalia N. Anastasopoulou, Alessandra Romano, Dominik Wolf, Kevin Nguyen, Lukas Van Den Ven, Alessia Di Pilla, Antonio Giordano, Oliver A. Cornely, Livio Pagano   +95 more
wiley   +1 more source

Determination of 116 Pharmaceuticals and Personal Care Products in Water by Ultra‐High Performance Liquid Chromatography‐Tandem Mass Spectrometry

Journal of Separation Science, Volume 48, Issue 12, December 2025.
ABSTRACT This study examined an improved and simplified method for solid‐phase extraction that provides rapid and accurate determination and identification of 116 pharmaceutical and personal care products (PPCPs) in an aqueous environment using ultra‐high performance liquid chromatography‐tandem mass spectrometry. The common active compounds include 22
Ming Xue, Yuwei Hong, Yanhong Lu, Shaoyin Liu, Haocheng Wu   +4 more
wiley   +1 more source