Results 61 to 70 of about 77,609 (253)
We performed a systematic review and meta-analysis on the effectiveness of ribavirin use for the prevention of infection and death of healthcare workers exposed to patients with Crimean-Congo hemorrhagic fever virus (CCHFV) infection. Splashes with blood
Önder Ergönül +7 more
doaj +1 more source
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Wang Chun Kwok +8 more
wiley +1 more source
Viral RNA at two stages of reovirus infection is required for the induction of necroptosis [PDF]
Necroptosis, a regulated form of necrotic cell death, requires the activation of the RIP3 kinase. Here, we identify that infection of host cells with reovirus can result in necroptosis.
Berger, Angela K +6 more
core +2 more sources
Novel Wide‐Spectrum Virucidal Lipid Nanoparticles
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins +10 more
wiley +1 more source
Background/Purpose: The major dose-limiting toxicity of ribavirin is hemolytic anemia. We investigated the incidence, risk factors and impact on virological response of anemia in chronic hepatitis C genotype 2 patients receiving sofosbuvir plus ribavirin
Chi-Ching Chen +10 more
doaj +1 more source
ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection. [PDF]
BACKGROUND & AIM:Whether inosine triphosphatase (ITPA) gene polymorphisms predict anemia during interferon-free therapy in chronic hepatitis C virus (HCV)-infected patients is unknown.
Tarik Asselah +16 more
doaj +1 more source
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Marion Retailleau +5 more
wiley +1 more source
Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source
The Neurological Effects of Ribavirin in Crimean-congo Hemorrhagic Fever Symptoms: A Systematic Review [PDF]
Background: Ribavirin is widely used in treating viral infections like Crimean-Congo hemorrhagic fever (CCHF), which is a severe disease with high morbidity and mortality.
Hossein Hatami +3 more
doaj
Higher pre‐treatment liver stiffness measurement (LSM) values, rather than post‐treatment values, independently predicts hepatocellular carcinoma after hepatitis C virus eradication, underscoring the need for continued surveillance in patients with elevated baseline LSM.
Takuma Nakatsuka +12 more
wiley +1 more source

