Results 61 to 70 of about 61,737 (200)
Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C. [PDF]
PLoS ONE, 2012 Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host's T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse
Bettina Langhans +6 more
doaj +1 more source
Journal of Viral Hepatitis, Volume 33, Issue 4, April 2026.ABSTRACT Approximately 8.8 million people are living with chronic hepatitis C virus (HCV) in Pakistan. We assessed factors related to health‐related quality of life (HRQoL) among the general population screened for HCV and calculated the national burden in quality‐adjusted life years (QALYs).
Siwaporn Niyomsri +24 more
wiley +1 more source
SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS
Сеченовский вестник, 2017 Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya +8 more
doaj
Journal of Viral Hepatitis, Volume 33, Issue 4, April 2026.ABSTRACT Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis worldwide. Whereas HEV infection is typically self‐limiting, rare cases of prolonged cholestasis have been reported. The underlying mechanisms remain unclear, though host genetic variation may contribute.
Montserrat Fraga +11 more
wiley +1 more source
Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. [PDF]
PLoS ONE, 2015 Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear.
Yang Wang +7 more
doaj +1 more source
Gastroenterology, 2002 BACKGROUND & AIMS Liver fibrosis is an important prognostic factor in patients with hepatitis C. The effect of pegylated (PEG) interferon alone or its combination with ribavirin on fibrosis has not been established.
T. Poynard +7 more
semanticscholar +1 more source
Cancer Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background The malignant glioma, as the most common and aggressive primary brain and spinal cord neoplasm, has shown limited responsiveness to available treatments, including tumor dissection, radiation, and chemotherapy. Thus, interferon type I, as a supplemental therapy, is added to the main therapies to overcome neoplasm resistance and ...
Nima Goudarzi +4 more
wiley +1 more source
PLoS ONE, 2019 Epithelial ovarian cancers are insidious pathologies that give a poor prognosis due to their late discovery and the increasing emergence of chemoresistance. Development of small pharmacological anticancer molecules remains a major challenge.
Anaïs Wambecke +8 more
doaj +1 more source
Gastroenterology, 2018 BACKGROUND & AIMS In phase 3 trials and real-world settings, smaller proportions of patients with genotype 3 hepatitis C virus (HCV) infection and cirrhosis have a sustained virologic response 12 weeks after treatment (SVR12) with the combination of ...
R. Esteban +21 more
semanticscholar +1 more source
Liver International Communications, Volume 7, Issue 1, March 2026.ABSTRACT Advances in hepatology—such as noninvasive serum biomarkers (e.g., Fibrosure since 2004), imaging techniques (e.g., MR Elastography since 2009 and FibroScan since 2013), and effective direct‐acting antivirals for the treatment of chronic hepatitis C—have likely influenced liver biopsy practices.
Nazire E. Albayrak +8 more
wiley +1 more source