Results 51 to 60 of about 33,368 (159)

Influence of Ribavirin on Mumps Virus Population Diversity

Viruses, 2021
Frequent mumps outbreaks in vaccinated populations and the occurrence of neurological complications (e.g., aseptic meningitis or encephalitis) in patients with mumps indicate the need for the development of more efficient vaccines as well as specific ...
Mirna Jurković, Anamarija Slović, Dubravko Forčić, Jelena Ivančić-Jelečki, Tanja Košutić-Gulija, Maja Jagušić   +5 more
doaj   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

The Neurological Effects of Ribavirin in Crimean-congo Hemorrhagic Fever Symptoms: A Systematic Review [PDF]

Caspian Journal of Neurological Sciences
Background: Ribavirin is widely used in treating viral infections like Crimean-Congo hemorrhagic fever (CCHF), which is a severe disease with high morbidity and mortality.
Hossein Hatami, Mohammad Javad Nasiri, Kimia Eyvani, Mobina Fatthy   +3 more
doaj  

Incidence, risk factors and impact on virological response of anemia in chronic genotype 2 hepatitis C receiving sofosbuvir plus ribavirin

Journal of the Formosan Medical Association, 2020
Background/Purpose: The major dose-limiting toxicity of ribavirin is hemolytic anemia. We investigated the incidence, risk factors and impact on virological response of anemia in chronic hepatitis C genotype 2 patients receiving sofosbuvir plus ribavirin
Chi-Ching Chen, Shui-Yi Tung, Kuo-Liang Wei, Chien-Heng Shen, Te-Sheng Chang, Wei-Ming Chen, Huang-Wei Xu, Chih-Wei Yen, Yi-Hsing Chen, Sheng-Nan Lu, Chao-Hung Hung   +10 more
doaj   +1 more source

Acute HEV Infection Is a Relevant Cause of Decompensation and ACLF in Patients With Liver Cirrhosis

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Hepatitis E virus (HEV) infection is very frequent in Europe with more than 2 million annual infections. Patients with liver cirrhosis may face an increased risk of suffering from acute‐on‐chronic liver failure (ACLF) due to HEV infection.
Katja Dinkelborg, Christian Niehaus, Birgit Bremer, Christine Wundes, Anja Tiede, Natalie Petruch, Katja Deterding, Anke R. M. Kraft, Björn Hartleben, Markus Cornberg, Heiner Wedemeyer, Patrick Behrendt, Benjamin Maasoumy   +12 more
wiley   +1 more source

Comparison of Interferon‐Based and Interferon‐Free Treatments on the Prognosis of Hepatocellular Carcinoma After Hepatitis C Virus‐Sustained Virological Response: A Multicenter Study

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Aim We examine the impact of interferon (IFN)‐based and IFN‐free treatment on the prognosis of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) sustained virological response (SVR). Methods Clinical information was collected on 311 cases of HCC after HCV‐SVR from 16 facilities affiliated with the Kyushu Liver Surgery Study Group ...
Shinji Itoh, Norifumi Iseda, Tomoharu Yoshizumi, Takao Ide, Hirokazu Noshiro, Hisamune Sakai, Toru Hisaka, Masao Nakashima, Hiroaki Nagano, Hirohisa Okabe, Hiromitsu Hayashi, Atsushi Miyoshi, Kenji Kitahara, Yuko Takami, Atsushi Nanashima, Tamotsu Kuroki, Yuichi Endo, Kohji Okamoto, Masatoshi Kajiwara, Masahiko Sakoda, Toru Beppu, Mitsuhisa Takatsuki, Susumu Eguchi   +22 more
wiley   +1 more source

Hepatitis C Virus Infection in the PERSIAN Guilan Cohort Study Population: Intrafamilial Transmission Incidence and Response to SOVODAK‐Based Therapy

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Hepatitis C virus (HCV) infection is one of the leading causes of liver‐related diseases such as cirrhosis and hepatocellular carcinoma. Despite ongoing efforts, no effective vaccine has been developed to date due to the virus's high mutation rate and extensive genetic variability. This study aimed to determine the prevalence of HCV
Farahnaz Joukar, Sara Yeganeh, Narges Eslami, Fariborz Mansour‐Ghanaei   +3 more
wiley   +1 more source

SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS

Сеченовский вестник, 2017
Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya, E. Ilyushenko, I. Belova, M. V. Sardushkin, N. Guznova, V. Piskunova, A. Dremuk, R. Ibragimova, A. V. Kukharenko   +8 more
doaj  

Seroprevalence of IgM and IgG Antibodies Directed Against Hepatitis E Virus in 4867 Blood Donors From Tyrol, Austria

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT There may be a risk of transmitting Hepatitis E Virus (HEV) through blood transfusions, however screening blood donors for HEV is not mandatory in Austria. We assessed the seroprevalence of anti–HEV antibodies among blood donors, thereby informing about the risk of HEV‐contaminated blood products.
Lisa Seekircher, Annelies Mühlbacher, Lena Tschiderer, Marco Amato, Manfred Astl, Harald Schennach, Anita Siller, Peter Willeit   +7 more
wiley   +1 more source

Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication

Cell Reports, 2019
Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and ...
Patrick M. Tate, Vincent Mastrodomenico, Bryan C. Mounce   +2 more
doaj   +1 more source