Results 111 to 120 of about 80,415 (299)

The role of riboflavin refeeding in reversing deficiency effects on duck reproductive performance and embryonic development

Animal Nutrition
Riboflavin (vitamin B2) is essential for poultry reproduction and embryonic development. Riboflavin deficiency adversely affects egg hatchability and embryonic survival, but whether these effects are reversible remains unclear. This study aimed to assess
Bo Zhang, Jie Wei, Junting Cao, Dongyan Zhang, Guangnan Xing, Yating Li, Ming Xie, Zhengkui Zhou, Shuisheng Hou, Jing Tang   +9 more
doaj   +1 more source

Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non‐small cell lung cancer cells: A drug repurposing study

Smart Molecules, EarlyView.
This study presents Delafloxacin repurposed as a DEPDC1‐targeting therapeutic aiming to suppress lung cancer progression. It highlights a novel strategy for lung cancer treatment with potential clinical applications. Abstract Emerging evidence highlights the oncogenic role of the Dishevelled, Egl‐10, and Pleckstrin domains containing 1 (DEPDC1) gene in
Noman Ali, Farishta Shafiq, Mishal Iftikhar, Muhammad Shahzad Zafar, Muhammad Shoaib   +4 more
wiley   +1 more source

De novo engineering riboflavin production Bacillus subtilis by overexpressing the downstream genes in the purine biosynthesis pathway

Microbial Cell Factories
Background Bacillus subtilis is widely used in industrial-scale riboflavin production. Previous studies have shown that targeted mutagenesis of the ribulose 5-phosphate 3-epimerase in B. subtilis can significantly enhance riboflavin production.
Chuan Liu, Miaomiao Xia, Huan Fang, Fan Xu, Sijia Wang, Dawei Zhang   +5 more
doaj   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Is the Generation of Active Vitamin B6 Dependent upon Riboflavin Status? New Analysis of Data from RCTs of Riboflavin Supplementation

Proceedings
Background and objectives: Riboflavin in the form flavin mononucleotide (FMN) acts as a cofactor for the pyridoxine phosphate oxidase required to generate pyridoxal 5′-phosphate (PLP), the active form of vitamin B6 in tissues.
Ryan Barlow, Helene McNulty, Catherine Hughes, Kristina Pentieva, Geraldine Horigan, Yvonne Lamers, Mary Ward   +6 more
doaj   +1 more source

RIBOFLAVIN [PDF]

British Journal of Ophthalmology, 1940
openaire   +2 more sources

Trace Levels of Triclosan May Affect Root Growth and Morphology in Cultivated Plants

Environmental Toxicology, EarlyView.
ABSTRACT Triclosan (TCS) is a micropollutant frequently detected in biosolids applied to agricultural soils. In soil solution—where it is potentially bioavailable to roots—it occurs at residual concentrations (ng L−1). Nevertheless, the ecotoxicological implications of TCS exposure in agricultural crops at these concentrations are still not fully ...
Lizandra de Souza Ratuchinski, Edson Araujo de Almeida, Matheus Cristiano Hermann Massariol, Diego Espirito Santo, Carmem Lúcia Henrich, Bianca da Cruz, Danielle Cristina da Silva de Oliveira, Gideã Taques Tractz, Regiane da Silva Gonzalez, Osvaldo Valarini Junior, Ana Paula Peron   +10 more
wiley   +1 more source

Proteomic insights into mycobacterial responses to elevated riboflavin reveal a role for flavin-sequestering proteins in flavin homeostasis

Frontiers in Tuberculosis
Riboflavin biosynthesis is essential for most microorganisms, yet its production is tightly regulated due to the potential toxic effect of riboflavin and its derivatives. While regulatory mechanisms for this process have been described in other organisms,
Nurudeen Oketade, Karen M. Dobos
doaj   +1 more source

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Investigations on the Luminescence Behavior of a Flavin Derivative Incorporated Into Al‐Based Metal–Organic Frameworks for the Sensing of Aromatic Nitro Compounds

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
For nitro group‐containing volatile compounds, a quenching effect was observed for DAMI@MOF, while the non‐nitro compounds chlorobenzene, toluene, and benzene yielded a fluorescence enhancement, rationalized by the relative energies of the derivative 8‐(dimethylamino)‐10‐methylisoalloxazine (DAMI) and analyte S1 states, with concomitant opposite ...
Annette Vollrath, Vasily Gvilava, Philipp Seiffert, Constantin Czekelius, Christoph Janiak   +4 more
wiley   +1 more source