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Biosynthesis of riboflavin

2001
The biosynthesis of one riboflavin molecule requires one molecule of GTP and two molecules of ribulose 5-phosphate. The imidazole ring of GTP is hydrolytically opened, yielding a 4,5-diaminopyrimidine that is converted to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione by a sequence of deamination, side chain reduction, and dephosphorylation ...
A, Bacher   +7 more
openaire   +2 more sources

Riboflavin

1986
Riboflavin deficiency diminishes the rate of growth of spontaneous tumors in experimental animals but enhances the carcinogenicity of specific drugs such as the azo dyes, which are degraded by a microsomal hydroxylase system requiring riboflavin. Human esophageal cancer has been epidemiologically associated with riboflavin deficiency, but the precise ...
openaire   +2 more sources

Riboflavin, Retbindin, and Riboflavin Transporters in the Retina

The retina is the most metabolically active tissue in the body. It harbors high levels of flavins due to their involvement as enzymatic co-factors in energy production. Flavins are delivered to the body via specific transporters, the ablation of which leads to riboflavin transporter deficiency (RTD) and ariboflavinosis in humans. RTD leads to embryonic
Xue Zhao   +2 more
openaire   +2 more sources

Riboflavin Deficiency and Preeclampsia

Obstetrics & Gynecology, 2000
To examine in a prospective study riboflavin deficiency as a predisposing factor for preeclampsia in a high-risk collective of pregnant women in Zimbabwe.At an antenatal clinic in Bulawayo, Zimbabwe, 154 women at increased risk for preeclampsia were observed prospectively until delivery.
J, Wacker   +5 more
openaire   +2 more sources

Microbial production of riboflavin: Biotechnological advances and perspectives

Metabolic Engineering, 2021
Xian Zhang, Guoqiang Xu, Zhiming Rao
exaly  

Regulation of riboflavin-metabolizing enzymes in riboflavin deficiency

American Journal of Physiology-Legacy Content, 1969
S, Fass, R S, Rivlin
openaire   +2 more sources

Riboflavin intake and status and relationship to anemia.

Nutrition Reviews, 2022
Tim J Green   +2 more
exaly  

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