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Riboflavin analogs and inhibitors of riboflavin biosynthesis
Applied Microbiology and Biotechnology, 2006Flavins are active components of many enzymes. In most cases, riboflavin (vitamin B(2)) as a coenzyme represents the catalytic part of the holoenzyme. Riboflavin is an amphiphatic molecule and allows a large variety of different interactions with the enzyme itself and also with the substrate.
Matthias, Mack, Simon, Grill
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1986
Riboflavin deficiency diminishes the rate of growth of spontaneous tumors in experimental animals but enhances the carcinogenicity of specific drugs such as the azo dyes, which are degraded by a microsomal hydroxylase system requiring riboflavin. Human esophageal cancer has been epidemiologically associated with riboflavin deficiency, but the precise ...
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Riboflavin deficiency diminishes the rate of growth of spontaneous tumors in experimental animals but enhances the carcinogenicity of specific drugs such as the azo dyes, which are degraded by a microsomal hydroxylase system requiring riboflavin. Human esophageal cancer has been epidemiologically associated with riboflavin deficiency, but the precise ...
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Journal of the American Medical Association, 1938
In the course of their studies on pellagra Goldberger and Lillie 1 used rats as experimental animals, and produced a characteristic deficiency disease. Ophthalmia and bilaterally symmetrical denuded areas were the most important symptoms, and these are still the most common and most characteristic.
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In the course of their studies on pellagra Goldberger and Lillie 1 used rats as experimental animals, and produced a characteristic deficiency disease. Ophthalmia and bilaterally symmetrical denuded areas were the most important symptoms, and these are still the most common and most characteristic.
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Archives of Ophthalmology, 1942
Since Warburg and Christian described the "yellow enzyme" in the year 1932, a number of papers have been published concerning riboflavin, which is an important part of the yellow enzyme. Chemists and biologists, however, were more successful in isolating riboflavin and in defining its various properties than physicians were in establishing its clinical
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Since Warburg and Christian described the "yellow enzyme" in the year 1932, a number of papers have been published concerning riboflavin, which is an important part of the yellow enzyme. Chemists and biologists, however, were more successful in isolating riboflavin and in defining its various properties than physicians were in establishing its clinical
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