Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease [PDF]
Nutrition & MetabolismBackground Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function.
Yanxian Wang +6 more
doaj +3 more sources
Role of riboflavin deficiency in malaria pathophysiology. [PDF]
PLoS PathogensThe emergence of resistance against antimalarials and insecticides poses a significant threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria to identify new targets and alternative therapies.
Shweta Sharma +2 more
doaj +4 more sources
Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE [PDF]
Redox BiologyThe retina, a metabolically active tissue, relies on adequate flavin levels for optimal function. Our previous research demonstrated that ablation of RTBDN, a retina-specific riboflavin binding protein, plays a pivotal role in maintaining flavin levels ...
Xue Zhao +3 more
doaj +3 more sources
Riboflavin Transporter Deficiency Type 2: Expanding the Phenotype of the Lebanese Founder Mutation p.Gly306Arg in the SLC52A2 Gene [PDF]
MetabolitesBackground: Riboflavin transporter deficiency type 2 is an ultra-rare, yet treatable, inborn error of metabolism. This autosomal recessive disorder is caused by pathogenic mutations in the SLC52A2 gene leading to progressive ataxia, polyneuropathy, and ...
Jean-Marc T. Jreissati +3 more
doaj +3 more sources
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis [PDF]
Redox Biology, 2022 Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha +7 more
doaj +2 more sources
Premature farrowing and stillbirths in two organic sow farms due to riboflavin deficiency [PDF]
Porcine Health Management, 2023 Background Riboflavin deficiency can lead to premature farrowing, stillborn piglets, weak-born piglets and neonatal death. Riboflavin (vitamin B2) is considered essential for reproductive function. The longer the period on riboflavin-deficient diets, the
Camilla Torreggiani +7 more
doaj +2 more sources
The Anemia of Human Riboflavin Deficiency [PDF]
Blood, 1965 Abstract 1. Riboflavin deficiency was induced in 8 adult males with a riboflavin deficient diet and a riboflavin antagonist, galactoflavin. 2. Each patient developed a normochromic normocytic anemia and reticulocytopenia. 3. The leukocyte counts and platelet counts remained within the normal range throughout
Montague Lane, Clarence P. Alfrey
openalex +4 more sources
Riboflavin in neurological diseases: therapeutic advances, metabolic insights, and emerging genetic strategies [PDF]
Frontiers in NeurologyBackgroundRiboflavin (vitamin B2), a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), is essential for mitochondrial function, redox balance, and neuronal viability.
Zhiming Tao +11 more
doaj +2 more sources
Identification of Riboflavin Metabolism Pathway in HepG2 Cells Expressing Genotype IV Swine Hepatitis E Virus ORF3 Protein [PDF]
Veterinary Sciences(1) Background: Hepatitis E (HE) is a novel zoonotic disease caused by hepatitis E virus (HEV). In particular, swine hepatitis E virus (SHEV) genotype IV is one of the main genotypes that infect humans.
Jing Tu +9 more
doaj +2 more sources
Effect of riboflavin deficiency on intestinal morphology, jejunum mucosa proteomics, and cecal microbiota of Pekin ducks. [PDF]
Anim Nutr, 2023 Xu Y +12 more
europepmc +2 more sources