Results 111 to 120 of about 917,291 (368)
Don't Fall for Tuning Parameters: Tuning-Free Variable Selection in High Dimensions With the TREX [PDF]
Lasso is a seminal contribution to high-dimensional statistics, but it hinges on a tuning parameter that is difficult to calibrate in practice. A partial remedy for this problem is Square-Root Lasso, because it inherently calibrates to the noise variance.
arxiv
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Lactic fermentation as a strategy to improve the nutritional and functional values of pseudocereals [PDF]
One of the greatest challenges is to reduce malnutrition worldwide while promoting sustainable agricultural and food systems. This is a daunting task due to the constant growth of the population and the increasing demands by consumers for functional ...
Gerez, Carla Luciana+2 more
core +1 more source
Probing for sparse and fast variable selection with model-based boosting [PDF]
We present a new variable selection method based on model-based gradient boosting and randomly permuted variables. Model-based boosting is a tool to fit a statistical model while performing variable selection at the same time. A drawback of the fitting lies in the need of multiple model fits on slightly altered data (e.g. cross-validation or bootstrap)
arxiv
Alfalfa flavonoids (AF) protected against Salmonella‐induced colitis by reducing inflammation and oxidative stress. AF inhibited the TLR4/IκB/NF‐κB/COX‐2 pathway and NLRP3 inflammasome, lowering pro‐inflammatory cytokines, while activating Keap1‐Nrf2 to boost antioxidants (e.g., HO‐1, NQO1, SOD, GPx), decreasing ROS‐driven oxidative stress.
Xiaoli Qin+11 more
wiley +1 more source
Erythrocyte Pathophysiology of Riboflavin deficiency in rats [PDF]
Pathophysiology of erythrocytes from riboflavin-deficient rats has been investigated. Riboflav in-deficiency was produced by feeding a riboflavin-deficient diet ad-libitum to weanling male Wistar specified pathogen-free, albino rats (40-SOg) housed ...
Hassan, FM
core +1 more source
Lactococcus lactis is capable of improving the riboflavin status in deficient rats [PDF]
Lactococcus lactis is a commonly used starter strain that can be converted from a vitamin B2 consumer into a vitamin B2 'factory' by over-expressing its riboflavin biosynthesis genes.
Burgess, Catherine M.+4 more
core +1 more source
Riboflavin Deficiency Caused by Treatment with Adriamycin.
The present study was undertaken to determine whether administration of adriamycin causes the depletion of riboflavin content. Rats received intraperitoneal injections of adriamycin (4 mg per kg body weight) for 6 consecutive days. Urinary riboflavin excretion began to increase after 2 days of treatment with adriamycin. Erythrocyte FAD levels decreased
Masayasu Sugiyama+4 more
openaire +4 more sources
IntroductionRiboflavin (vitamin B2) is absorbed in the small intestine by the human riboflavin transporters RFVT1 and RFVT3. A third riboflavin transporter (RFVT2) is expressed in the brain.
B. Jaeger, A. Bosch
semanticscholar +1 more source