Results 21 to 30 of about 913,849 (270)

Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice. [PDF]

Sci Rep, 2020
Riboflavin transporter 3 (RFVT3), encoded by the SLC52A3 gene, is important for riboflavin homeostasis in the small intestine, kidney, and placenta. Our previous study demonstrated that Slc52a3 knockout (Slc52a3−/−) mice exhibited neonatal lethality and ...
Jin C, Yonezawa A, Yoshimatsu H, Imai S, Koyanagi M, Yamanishi K, Nakagawa S, Itohara K, Omura T, Nakagawa T, Nagai J, Matsubara K.   +11 more
europepmc   +2 more sources

Anaemia during pregnancy: could riboflavin deficiency be implicated? [PDF]

Anaemia affects more than 36% of all pregnancies globally and is associated with significant maternal and neonatal morbidity and mortality. Iron deficiency is widely recognised as the most common nutritional cause of anaemia but other nutrient ...
Bethany Duffy, Helene McNulty, Mary Ward, Kristina Pentieva   +3 more
openalex   +4 more sources

Revitalising Riboflavin: Unveiling Its Timeless Significance in Human Physiology and Health [PDF]

Foods
Since the early twentieth century, research on vitamins has revealed their therapeutic potential beyond their role as essential micronutrients. Riboflavin, known as vitamin B2, stands out for its unique characteristics.
M. Ângela Aragão, Lara Pires, Celestino Santos-Buelga, Lillian Barros, Ricardo C. Calhelha   +4 more
doaj   +2 more sources

Characterization of two ETFDH mutations in a novel case of riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency

Lipids in Health and Disease, 2018
Background Deficiency of electron transfer flavoprotein dehydrogenase (ETFDH) is associated with multiple acyl-CoA dehydrogenase deficiency (MADD).
Sara Missaglia, Daniela Tavian, Laura Moro, Corrado Angelini   +3 more
doaj   +2 more sources

Maternal riboflavin deficiency [PDF]

Definitions, 2020
Maternal riboflavin deficiency is a rare, genetic disorder of metabolite absorption or transport characterized by persistently decreased riboflavin serum levels due to a primary genetic defect in the mother and which leads to clinical and biochemical ...

openalex   +2 more sources

Late-onset riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (MADD): case reports and epidemiology of ETFDH gene mutations

BMC Neurology, 2019
Background Multiple acyl-CoA dehydrogenase deficiency (MADD) is a riboflavin-responsive lipid-storage myopathy caused by mutations in the EFTA, EFTB or ETFDH genes.
Wei Chen, Youqiao Zhang, Yifeng Ni, Shaoyu Cai, Xin Zheng, Frank L. Mastaglia, Jingshan Wu   +6 more
doaj   +2 more sources

Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells. [PDF]

Sci Rep, 2017
Riboflavin deficiency is widespread in many regions over the world, especially in underdeveloped countries. In this study, we investigated the effects of riboflavin deficiency on protein expression profiles in HepG2 cells in order to provide molecular ...
Xin Z, Pu L, Gao W, Wang Y, Wei J, Shi T, Yao Z, Guo C.   +7 more
europepmc   +2 more sources

Antioxidant Amelioration of Riboflavin Transporter Deficiency in Motoneurons Derived from Patient-Specific Induced Pluripotent Stem Cells [PDF]

International Journal of Molecular Sciences, 2020
Mitochondrial dysfunction is a key element in the pathogenesis of neurodegenerative disorders, such as riboflavin transporter deficiency (RTD). This is a rare, childhood-onset disease characterized by motoneuron degeneration and caused by mutations in ...
Chiara Marioli, Valentina Magliocca, Stefania Petrini, Alessia Niceforo, Rossella Borghi, Sara Petrillo, Piergiorgio La Rosa, Fiorella Colasuonno, Tiziana Persichini, Fiorella Piemonte, Keith Massey, Marco Tartaglia, Sandra Moreno, Enrico Bertini, Claudia Compagnucci   +14 more
openalex   +2 more sources

Riboflavin Deficiency in Rats Decreases de novo Formate Production but Does Not Affect Plasma Formate Concentration. [PDF]

J Nutr, 2017
Background: The one-carbon metabolism pathway is highly dependent on a number of B vitamins in order to provide one-carbon units for purine and thymidylate biosynthesis as well as homocysteine remethylation.
MacMillan L, Lamarre SG, daSilva RP, Jacobs RL, Brosnan ME, Brosnan JT.   +5 more
europepmc   +2 more sources

Causes and Clinical Sequelae of Riboflavin Deficiency.

Annual review of nutrition, 2023
Riboflavin, in its cofactor forms flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), plays fundamental roles in energy metabolism, cellular antioxidant potential, and metabolic interactions with other micronutrients, including iron ...
H. McNulty, K. Pentieva, M. Ward
semanticscholar   +1 more source