Results 61 to 70 of about 19,244 (296)

Maternal vitamin deficiency mimicking multiple acyl-CoA dehydrogenase deficiency on newborn screening

Molecular Genetics and Metabolism Reports, 2021
Background: In infancy multiple acyl-CoA dehydrogenase deficiency (MADD) is commonly a severe inherited metabolic disease caused by genetic defects in electron transfer flavoprotein (ETF) or ETF ubiquinone oxidoreductase.
Gwendolyn Gramer, Georg F. Hoffmann, Julia B. Hennermann   +2 more
doaj  

A Historical Cohort Study on the Efficacy of Glucocorticoids and Riboflavin Among Patients with Late-onset Multiple Acyl-CoA Dehydrogenase Deficiency

Chinese Medical Journal, 2016
Background: Late-onset multiple acyl-CoA dehydrogenase deficiency (MADD) is the most common type of lipid storage myopathies in China. Most patients with late-onset MADD are well responsive to riboflavin.
Xin-Yi Liu, Zhi-Qiang Wang, Dan-Ni Wang, Min-Ting Lin, Ning Wang   +4 more
doaj   +1 more source

Factors associated with the severity of COVID‐19 outcomes in people with neuromuscular diseases: Data from the International Neuromuscular COVID‐19 Registry

European Journal of Neurology, Volume 30, Issue 2, Page 399-412, February 2023., 2023
Abstract Background and purpose Clinical outcome information on patients with neuromuscular diseases (NMDs) who have been infected with SARS‐CoV‐2 is limited. The aim of this study was to determine factors associated with the severity of COVID‐19 outcomes in people with NMDs.
Chiara Pizzamiglio, Robert D. S. Pitceathly, Michael P. Lunn, Stefen Brady, Fabiola De Marchi, Lucia Galan, Jeannine M. Heckmann, Alejandro Horga, Maria J. Molnar, Acary S. B. Oliveira, Wladimir B. V. R. Pinto, Guido Primiano, Ernestina Santos, Benedikt Schoser, Serenella Servidei, Paulo V. Sgobbi Souza, Vishnu Venugopalan, Michael G. Hanna, Mazen M. Dimachkie, Pedro M. Machado, for the Neuromuscular Diseases and COVID‐19 Study Group, Albert Lim, Amar Elsaddig, Ana Juanatey, Ana Romeiro, Andreas Themistocleous, Annamaria Kiss‐Csenki, Antonio Guerrero Sola, Anuja Patil, Ashish Duggal, Carolyn Gabriel, Charles Marshall, Christopher Record, Claire Allen, David Bearden, DeviPriya Rathna Sabapathi, Dileep R, Domizia Vecchio, Edward Newman, Edwin Eshun, Eng C. Foo, Enrico Bugiardini, Georgina Burke, Gita Ramdharry, Gràinne S. Gorman, Guru Kumar, Harri Sivasathiaseelan, Igor Braga Farias, Izelle Smuts, James Holt, Jan T. Groothuis, Jane Pritchard, Jasmine Wall, Josep Gamez, K. J. S. Shakthi, Kate Wannop, Kathryn Brennan, Lillian Saavedra, Lisa Clayton, Liz Househam, Mariola Skorupinska, Matilde Laura, Matteo Ciocca, Maya Zosmer, Megha Dhamne, Michelangelo Mancuso, Mirian Janssen, Olimpia Musumeci, Olivia Price, Patrick F. Chinnery, Philip Ambrose, Puja R. Mehta, Rhys H. Thomas, Rita Horvath, Robert McFarland, Ross Nortley, Ross W. Paterson, Ruth Geraldes, Ryan Keh, Saara Neshuku, Sandhya Sasidharan, Sarath Menon R, Sharika Raga, Simon Rinaldi, Sireesha Yareeda, Soaham Desai, Sridharan Ramaratnam, Stephen Keddie, Taylor Watson‐Fargie, Teresinha Evangelista, Valeria Sansone, Victoria Nesbitt, William L. Macken, Yavuz Oktay   +93 more
wiley   +1 more source

Finite groups of arbitrary deficiency [PDF]

Bull. London Math. Soc. 49 (2017) 1100-1104, 2017
The deficiency of a group is the maximum over all presentations for that group of the number of generators minus the number of relators. Every finite group has non-positive deficiency. We show that every non-positive integer is the deficiency of a finite group -- in fact, of a finite $p$-group for every prime $p$.
arxiv   +1 more source

Production of diverse brGDGTs by Acidobacterium Solibacter usitatus in response to temperature, pH, and O2 provides a culturing perspective on brGDGT proxies and biosynthesis

Geobiology, Volume 21, Issue 1, Page 102-118, January 2023., 2023
Abstract Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are bacterial membrane lipids that are frequently employed as paleoenvironmental proxies because of the strong empirical correlations between their relative abundances and environmental temperature and pH.
Toby A. Halamka, Jonathan H. Raberg, Jamie M. McFarlin, Adam D. Younkin, Christopher Mulligan, Xiao‐Lei Liu, Sebastian H. Kopf   +6 more
wiley   +1 more source

Dietary supplements for aggressive behaviour in people with intellectual disabilities: A randomised controlled crossover trial

Journal of Applied Research in Intellectual Disabilities, Volume 36, Issue 1, Page 122-131, January 2023., 2023
Abstract Background Aggressive incidents are common in people with intellectual disabilities. Therefore, we aimed to assess whether supplementation of multivitamins, minerals, and omega‐3 fatty acids (FA) reduces aggressive incidents. Methods We conducted a randomised, triple blind, placebo controlled, single crossover intervention trial.
David A. A. Gast, Robert Didden, Johanna J. Westera, Ondine van de Rest, Albert M. van Hemert, Erik J. Giltay   +5 more
wiley   +1 more source

Reaction of the NAD(P)H:flavin oxidoreductase from Escherichia coli with NADPH and riboflavin: identification of intermediates [PDF]

Biochemistry, American Chemical Society, 1998, 37, pp.11879-87, 2014
Flavin reductase catalyzes the reduction of free flavins by NAD(P)H. As isolated, Escherichia coli flavin reductase does not contain any flavin prosthetic group but accommodates both the reduced pyridine nucleotide and the flavin substrate in a ternary complex prior to oxidoreduction.
arxiv  

Riboflavin deficiency and the preterm infant [PDF]

Pediatric Research, 1984
Riboflavin (B2) plays a central role in intermediary metabolism and energy release; little is known about riboflavin requirements or pathophysiological consequences of deficiency states in preterm (PT) infants. 68 infants were allocated randomly to diets including human milk or a preterm formula containing 1.8 mg riboflavin/1.
Bates Cj, Powers Hj, Duerden J, Lucas A
openaire   +1 more source

Investigation of a broad‐spectrum micronutrient formulation as a possible precipitant of pharmacokinetic micronutrient–drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Aims Daily broad‐spectrum micronutrients are being used by the general public and formulations are receiving research interest in mental health settings. Despite concerns about combining medicines and broad‐spectrum micronutrients in mental health care, there have not been any formal evaluations of potential interactions.
Bess M. Kew, Matthew P. Doogue, Richard McNeill, Mei Zhang, Julia J. Rucklidge, Christopher M. Frampton, Roger T. Mulder, Ben Beaglehole   +7 more
wiley   +1 more source

A juvenile ALS‐like phenotype dramatically improved after high‐dose riboflavin treatment

Annals of Clinical and Translational Neurology, 2020
Riboflavin transporter deficiency (RTD) was recently characterized as a cause of genetic recessive childhood‐onset motor neuron disease (MND) with hearing loss, formerly described as Brown‐Vialetto‐Van‐Lear syndrome.
Christophe Carreau, Timothée Lenglet, Isabelle Mosnier, Ghizlene Lahlou, Guillaume Fargeot, Nicolas Weiss, Sophie Demeret, François Salachas, Alice Veauville‐Merllié, Cécile Acquaviva, Yann Nadjar   +10 more
doaj   +1 more source