Results 81 to 90 of about 14,737 (236)

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

open access: yesInterdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang   +13 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş   +4 more
wiley   +1 more source

Risk factors for anaemia among women and their young children hospitalised with suspected thiamine deficiency in northern Lao PDR

open access: yesMaternal and Child Nutrition
Anaemia among women and young children remains a major public health concern. This secondary study describes the anaemia prevalence among young hospitalised children and their mothers in northern Lao People's Democratic Republic and explores possible ...
Sonja Y. Hess   +8 more
doaj   +1 more source

Flavin-dependent NmoA catalyzes oxidation of elemental selenium: Regulation by riboflavin synthesis and role in enhancing soil selenium bioavailability

open access: yesEnvironment International
Oxidation of elemental selenium (Se(0)) to Se oxyanions is essential to improve soil Se availability and plant uptake, addressing Se deficiency for one billion people worldwide. However, its molecular mechanism was unclear. Proteomic analysis showed Se(0)
Yiting Wang   +6 more
doaj   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

open access: yesMovement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska   +6 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Genotype-environment interaction drives the onset of riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency in carriers of single heterozygous ETFDH variants

open access: yesCell Communication and Signaling
Background Riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (RR-MADD) is an autosomal recessive disorder of fatty acid oxidation predominantly caused by variants in the ETFDH gene.
Jing Ma   +12 more
doaj   +1 more source

A case report of riboflavin transporter deficiency: A novel heterozygous pathogenic variant in the SLC52A3 gene

open access: yesMolecular Genetics and Metabolism Reports
Riboflavin transporter deficiency (RTD) is a neurodegenerative disorder that presents from infancy to adulthood with a progressive axonal neuropathy characterized by a variety of neurologic symptoms including hearing loss, weakness, bulbar palsy, and ...
Elizabeth S. Tranel   +6 more
doaj   +1 more source

Binder Design in Extrusion‐Based 3D Printing of Electrodes: Enhancing Printability and Electrochemical Performance in Energy Storage Devices

open access: yesSmall, EarlyView.
Binder design plays a pivotal role in extrusion‐based 3D printing of energy storage electrodes by simultaneously governing ink printability and electrochemical performance. This review examines how diverse binder materials and design strategies are employed to enable printability while addressing key electrochemical challenges in energy storage devices,
Akesh Manimendra Badalge   +7 more
wiley   +1 more source

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