Results 71 to 80 of about 19,244 (296)

Atomic Structures of Riboflavin (Vitamin B2) and its Reduced Form with Bond Lengths Based on Additivity of Atomic Radii [PDF]

arXiv, 2008
It has been shown recently that chemical bond lengths, in general, like those in the components of nucleic acids, caffeine related compounds, all essential amino acids, methane, benzene, graphene and fullerene are sums of the radii of adjacent atoms constituting the bond.
arxiv  

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

ChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout, Marie‐Christine Maurel   +1 more
wiley   +1 more source

Fluorescence Spectroscopy of Flour Fractions and Dough: Analysis of Spectral Differences and Potential to Improve Wheat Quality Prediction

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Spectroscopy of wheat kernels and flour has been used as a rapid tool to assess wheat quality, but predictions still lack in accuracy for most quality parameters except for protein content. To enable an improved prediction of further quality characteristics, new approaches are needed.
Denise Ziegler, Lukas Buck, Katharina Anne Scherf, Lutz Popper, Bernd Hitzmann   +4 more
wiley   +1 more source

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility

Cell Reports, 2021
Summary: Ablation of Slc22a14 causes male infertility in mice, but the underlying mechanisms remain unknown. Here, we show that SLC22A14 is a riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa mid-piece and show by ...
Wenhua Kuang, Jie Zhang, Zhou Lan, R.N.V. Krishna Deepak, Chao Liu, Zhilong Ma, Lili Cheng, Xinbin Zhao, Xianbin Meng, Weihua Wang, Xueying Wang, Lina Xu, Yupei Jiao, Qi Luo, Ziyi Meng, Kehkooi Kee, Xiaohui Liu, Haiteng Deng, Wei Li, Hao Fan, Ligong Chen   +20 more
doaj  

Myopathy with Complex I Deficiency: Riboflavin Carnitine Therapy

Pediatric Neurology Briefs, 1991
A six year old boy with progressive myopathy and motor neuropathy associated with complex I deficiency is reported from the Institutes of Neurology, Pediatrics and Cell Biology, St. Radboud University Hospital, Nijmegen, Netherlands.
J Gordon Millichap
doaj   +1 more source

Confidence Intervals and Hypothesis Testing for High-Dimensional Regression [PDF]

arXiv, 2013
Fitting high-dimensional statistical models often requires the use of non-linear parameter estimation procedures. As a consequence, it is generally impossible to obtain an exact characterization of the probability distribution of the parameter estimates. This in turn implies that it is extremely challenging to quantify the \emph{uncertainty} associated
arxiv  

Riboflavin-responsive complex I deficiency

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1995
Three patients from a large consanguineous family, and one unrelated patient had exercise intolerance since early childhood and improved by supplementation with a high dosage of riboflavin. This was confirmed by higher endurance power in exercise testing.
Jan M. Bogaard, I. E. M. Luyt-Houwen, L. Kuyt, Henk D. Bakker, H.F.M. Busch, Hans R. Scholte   +5 more
openaire   +3 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Wolbachia causes cytoplasmic incompatibility but not male‐killing in a grain pest beetle

Molecular Ecology, Volume 31, Issue 24, Page 6570-6587, December 2022., 2022
Abstract The endosymbiotic Wolbachia is one of the most common intracellular bacteria known in arthropods and nematodes. Its ability for reproductive manipulation can cause unequal inheritance to male and female offspring, allowing the manipulator to spread, but potentially also impact the evolutionary dynamics of infected hosts.
Julian S. T. Kiefer, Gerrit Schmidt, Ronja Krüsemer, Martin Kaltenpoth, Tobias Engl   +4 more
wiley   +1 more source

Probing for sparse and fast variable selection with model-based boosting [PDF]

arXiv, 2017
We present a new variable selection method based on model-based gradient boosting and randomly permuted variables. Model-based boosting is a tool to fit a statistical model while performing variable selection at the same time. A drawback of the fitting lies in the need of multiple model fits on slightly altered data (e.g. cross-validation or bootstrap)
arxiv