Results 101 to 110 of about 145,501 (289)

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

Advanced Healthcare Materials, EarlyView.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico, Irene Chiesa, Angela Toffano, Alessio Esposito, Piera Mancini, Chiara Magliaro, Angeliki Louvi, Carmelo De Maria, Marco Onorati   +8 more
wiley   +1 more source

Inducible expression of the gene of Zinnia elegans coding for extracellular ribonuclease in Nicotiana tabacum plants

Biologia Plantarum, 2012
The gene of Zinnia elegans L. coding for S-like extracellular ribonuclease (ZRNase II) was used to produce transgenic tobacco plants with an increased ribonuclease activity. The protein-coding part of ZRNase II included the signal peptide sequence so the
E. A. Trifonova, A. V. Romanova, S. S. Sangaev, M. V. Sapotsky, V. I. Malinovsky, A. V. Kochetov   +5 more
doaj   +1 more source

Molecular dynamics of C-peptide of ribonuclease A studied by replica-exchange Monte Carlo method and diffusion theory

, 2003
Generalized-ensemble algorithm and diffusion theory have been combined in order to compute the dynamical properties monitored by nuclear magnetic resonance experiments from efficient and reliable evaluation of statistical averages. Replica-exchange Monte
Ayori Mitsutake, Brüschweiler, Cavanagh, Fausti, Giovanni La Penna, Gō, Hansmann, Hukushima, Koradi, Kostov, La Penna, La Penna, Lipari, Masato Masuya, Mitsutake, Mitsutake, Okamoto, Okamoto, Okamoto, Okamoto, Ooi, Osterhout, Pastor, Perico, Rose, Schaefer, Shoemaker, Sippl, Soman, Sugita, Sugita, Tilton, Yuko Okamoto   +32 more
core   +1 more source

Molecular recognition betweenEscherichia colienolase and ribonuclease E [PDF]

, 2010
Salima Nurmohamed, Adam R. McKay, Carol V. Robinson, Ben F. Luisi   +3 more
openalex   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum

Microbiology Spectrum
To explore the influence of storage temperature and time on the stability of different concentrations of hepatitis C virus nucleic acid (HCV RNA) samples and to provide data reference for laboratory quality control.
Ya-pei Wang, Shu-wen Yang, Fan Jia, Wei Wang, Xue Xu, Yi-xuan Wang, Jing-feng Bi, Bo-an Li   +7 more
doaj   +1 more source

Influence of gibberellic acid on hydrolytic enzymes activity in germinating different-aged lupin seeds

Acta Societatis Botanicorum Poloniae, 2015
The influence of GA3 -on the germination of different-aged lupin seed and α-amylase, protease and ribonuclease activity in the embryonic axis and cotyledons of these seeds were investigated after 24, 48, 72 and 96 h of germination. GA3 treatment of older
T. Mierzwińska
doaj   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Influence of IAA, kinetin and ABA on ribonuclease activity in the embryonal roots of two barley (Hordeum vulgare L.) cultivars

Acta Agrobotanica, 2013
IAA, kinetin and ABA in a concentration of 10-7M did not cause major changes in the activity of ribonuclease in both cultivars. IAA and kinetin in a concentration of 10-5M lowered the activity of the tested enzyme, more in the 'Union' than in the ...
Halina Skoczek
doaj   +1 more source