Results 191 to 200 of about 145,501 (289)

The structure and allelic diversity of the self-incompatibility locus (S-locus) in diploid potatoes inferred from genome sequences and transcriptome data from styles and pollen. [PDF]

Plant Genome
Ames M, Halterman D, Bethke PC.
europepmc   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

The ribonuclease E regulator RebA is essential for diazotrophic growth in the cyanobacterium <i>Anabaena</i> PCC 7120. [PDF]

mLife
Liu S, Wang Z, Lin G, Li W, Zeng X, Zhang JY, Zhang CC.   +6 more
europepmc   +1 more source

Modification of the Methionine Residue in the Peptide Component of Ribonuclease-S

, 1960
Paul J. Vithayathil, Frederic M. Richards   +1 more
openalex   +1 more source

A novel mechanism of ribonuclease regulation: GcvB and Hfq stabilize the mRNA that encodes RNase BN/Z during exponential phase [PDF]

, 2019
Hua Chen, Angelica Previero, Murray P. Deutscher   +2 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Ribonuclease RNase Z is an evolutionarily conserved deAMPylase. [PDF]

Proc Natl Acad Sci U S A
Mukherjee M, Pon A, Goldberg T, Pawłowski K, Sreelatha A.   +4 more
europepmc   +1 more source

Properties and Conformation of the Histidine Residues at the Active Site of Ribonuclease

, 1963
Arthur M. Crestfield, William H. Stein, Stanford Moore   +2 more
openalex   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

C‑Nucleosides Stabilize RNA by Reducing Nucleophilicity at 2'-OH. [PDF]

ACS Cent Sci
Banerjee D, Xiao L, Thacker PS, Kundu J, Manoharan M, Kool ET.   +5 more
europepmc   +1 more source