Results 231 to 240 of about 156,401 (384)

Purification and Properties of Ribonuclease III from Escherichia coli

, 1968
Hugh D. Robertson, Robert E. Webster, Norton D. Zinder   +2 more
openalex   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation. [PDF]

J Virol
Zhou D, Xu M, Liu Q, Xin R, Cui G, Ding L, Liu X, Zhang X, Yan T, Zhou J, He S, Yang L, Xiang B, Cheng Z.   +13 more
europepmc   +1 more source

Properties and Conformation of the Histidine Residues at the Active Site of Ribonuclease

, 1963
Arthur M. Crestfield, William H. Stein, Stanford Moore   +2 more
openalex   +1 more source

ON THE ACTION OF RIBONUCLEASE

Journal of Biological Chemistry, 1951
Krikor. Seraidarian, Liselotte. Hecht, Ricardo Cubiles, Nepomuk Zöllner, Nancy. Strickler, Maria. Seraidarian, S.J. Thannhauser, Gerhard Schmidt   +7 more
openaire   +3 more sources

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Angiogenin-catalyzed cleavage within tRNA anticodon-loops identified by cP-RNA-seq. [PDF]

Biosci Biotechnol Biochem
Shigematsu M, Matsubara R, Gumas J, Kawamura T, Kirino Y.   +4 more
europepmc   +1 more source

On the Structure of Bovine Pancreatic Ribonuclease B

, 1964
Thomas H. Plummer, C.H.W. Hirs
openalex   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Molecular basis for the calcium-dependent activation of the ribonuclease EndoU. [PDF]

Nat Commun
Malard F, Dias K, Baudy M, Thore S, Vialet B, Barthélémy P, Fribourg S, Karginov FV, Campagne S.   +8 more
europepmc   +1 more source