Results 221 to 230 of about 132,332 (305)

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

CARF-dependent preferential RNA cleavage by Csm6 increases drug susceptibility of mycobacteria. [PDF]

Nucleic Acids Res
Wei W, Gao CH, Jiang X, Qiao J, Zhang L, Yan Y, Zhao G, Yang K, Yan J, Yang M.   +9 more
europepmc   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

Advanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li, Xiangmin Tan, Yaran Liu, Yongquan He, Bo Yuan, Ping Wang, Guangzhi Ma, Mengzhe Guo, Jian Zhou, Qiang Sun   +9 more
wiley   +1 more source

Antibacterial and proteomic profiling of Morus alba extract against methicillin-resistant Staphylococcus aureus. [PDF]

PeerJ
Reamtong O, Swangsri T, Thiangtrongjit T, Saralamba S, Rakthong P, Thaenkham U, Saralamba N.   +6 more
europepmc   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans. [PDF]

Nat Commun
Kyriakakis E, Medde C, Ritz D, Fucile G, Schmidt A, Spang A.   +5 more
europepmc   +1 more source

Nascent polypeptide chains on mitochondrial ribosomes and their integration into the inner membrane [PDF]

, 1974
Kroon, Albertus M., Michel, Rainer, Neupert, Walter, Saccone, C.   +3 more
core  

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

Advanced Science, EarlyView.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang, Wen Sun, Ting Xiao, Yali Wang, Xianlan Wu, Huiyou Chen, Ming Chen, Jun Zhang   +7 more
wiley   +1 more source

Pseudouridine residues as substrates for serum ribonucleases. [PDF]

RNA
Gutierrez CS, Silkenath B, Kojasoy V, Pich JA, Lim DC, Raines RT.   +5 more
europepmc   +1 more source

Ribonuclease P. Postscript

Journal of Biological Chemistry, 1990
openaire   +2 more sources