Results 21 to 30 of about 167,361 (378)

Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate

open access: yesbioRxiv, 2021
Ribonucleoprotein bodies are exemplars of membraneless biomolecular condensates that can form via spontaneous or driven phase transitions. The fungal protein Whi3 forms ribonucleoprotein condensates with different RNA molecules, and these condensates are
Ian Seim   +6 more
semanticscholar   +1 more source

Proteins Rpr2 and Pop3 increase the activity and thermal stability of yeast RNase P

open access: yesRNA Biology, 2023
RNA-based enzyme RNase P is a ribonucleoprotein complex responsible primarily for 5’-maturation of tRNAs. S. cerevisiae RNase P comprises a catalytic RNA component and nine proteins. The assembly and maturation of S.
Anna Perederina   +2 more
doaj   +1 more source

Compartmentalized oskar degradation in the germ plasm safeguards germline development

open access: yeseLife, 2020
Partitioning of mRNAs into ribonucleoprotein (RNP) granules supports diverse regulatory programs within the crowded cytoplasm. At least two types of RNP granules populate the germ plasm, a cytoplasmic domain at the posterior of the Drosophila oocyte and ...
Catherine E Eichler   +3 more
doaj   +1 more source

A Comprehensive Roadmap Towards the Generation of an Influenza B Reporter Assay Using a Single DNA Polymerase-Based Cloning of the Reporter RNA Construct

open access: yesFrontiers in Microbiology, 2022
The mini-genome reporter assay is a key tool for conducting RNA virus research. However, procedural complications and the lack of adequate literature pose a major challenge in developing these assay systems.
Nandita Kedia   +2 more
doaj   +1 more source

Biogenesis of telomerase ribonucleoproteins [PDF]

open access: yesRNA, 2012
Telomerase adds simple-sequence repeats to the ends of linear chromosomes to counteract the loss of end sequence inherent in conventional DNA replication. Catalytic activity for repeat synthesis results from the cooperation of the telomerase reverse transcriptase protein (TERT) and the template-containing telomerase RNA (TER).
Emily D, Egan, Kathleen, Collins
openaire   +2 more sources

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

open access: yes, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

Structure of spliceosomal ribonucleoproteins [PDF]

open access: yesF1000 Biology Reports, 2010
Splicing of the precursors of eukaryotic mRNA and some non-coding RNAs is catalyzed by the 'spliceosome', which comprises five RNA-protein complexes (small nuclear ribonucleoproteins, or snRNPs) that assemble in an ordered manner onto precursor-mRNAs. Much progress has been made in determining the gross morphology of spliceosomal assembly intermediates.
Krummel, Daniel Aaron Pomeranz   +2 more
openaire   +2 more sources

Budding of a Retrovirus: Some Assemblies Required

open access: yesViruses, 2020
One of the most important steps in any viral lifecycle is the production of progeny virions. For retroviruses as well as other viruses, this step is a highly organized process that occurs with exquisite spatial and temporal specificity on the cellular ...
Kevin M. Rose   +2 more
doaj   +1 more source

A novel experimental approach for the selective isolation and characterization of human RNase MRP

open access: yesRNA Biology, 2022
RNase MRP is a ribonucleoprotein complex involved in the endoribonucleolytic cleavage of different RNAs. Mutations in the RNA component of the RNP are the cause of cartilage hair hypoplasia.
Merel Derksen   +5 more
doaj   +1 more source

Synthetic gRNA/Cas9 Ribonucleoprotein Inhibits HIV Reactivation and Replication

open access: yesViruses, 2022
The current antiretroviral therapy (ART) for human immunodeficiency virus (HIV) can halt viral replication but cannot eradicate HIV infection because proviral DNA integrated into the host genome remains genetically silent in reservoir cells and is ...
Sushant Khanal   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy